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suck abstract from ncbi


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pmid2788704      J+Exp+Med 1989 ; 170 (3): 1045-50
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  • Borna disease, a progressive meningoencephalomyelitis as a model for CD4+ T cell-mediated immunopathology in the brain #MMPMID2788704
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  • J Exp Med 1989[Sep]; 170 (3): 1045-50 PMID2788704show ga
  • A homogeneous T cell line NM1 with Borna disease (BD) virus reactivity could be established. The NM1 cells have been characterized as CD4+ T cells. Adoptive transfer revealed that this MHC class II-restricted immune cell is responsible for the immunopathological effect leading to BD, a progressive meningoencephalomyelitis.
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