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10.1186/1743-422X-4-9 http://scihub22266oqcxt.onion/10.1186/1743-422X-4-9 C1781424!1781424 !17224071     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\17224071 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Virol+J 2007 ; 4 (ä): 9 Nephropedia Template TP {{tp|p=17224071 |t=2007. The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages |pdf=|usr=}}{{17224071 }} gab.com Text The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages JO: Virol J http://www.kidney.de/pget.php?&tw=1&pmid=17224071 #FOAvip With the prospect of another pandemic Influenza fresh in our consciousness, the pathogenic nature of the Influenza A virus and its ability to induce high rates of mortality are ever more pertinent. Recently a novel protein encoded by an alternate reading frame in the PB1 Gene segment of Influenza A virus has been discovered and in turn shown to enhance viral virulence in a mouse model 1. This protein has been shown to specifically target and destroy alveolar macrophages 2. This review suggests that this protein, present in all previous pandemic strains, may reappear as a virulence factor in a subsequent pandemic strain. This PB1-F2 protein will enhance the mortality rate of the virus by increasing the likelihood of a secondary bacterial infection, which is the primary cause of death to a patient infected with Influenza A. Twit Text FOAVip The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages ????Virol J http://www.kidney.de/pget.php?&tw=1&pmid=17224071 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=17224071 #FOAvip English Wikipedia <ref>{{Cite pmid|17224071 }}</ref> The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages #MMPMID17224071 Coleman JR Virol J 2007[Jan]; 4 (ä): 9 PMID17224071 show ga With the prospect of another pandemic Influenza fresh in our consciousness, the pathogenic nature of the Influenza A virus and its ability to induce high rates of mortality are ever more pertinent. Recently a novel protein encoded by an alternate reading frame in the PB1 Gene segment of Influenza A virus has been discovered and in turn shown to enhance viral virulence in a mouse model 1. This protein has been shown to specifically target and destroy alveolar macrophages 2. This review suggests that this protein, present in all previous pandemic strains, may reappear as a virulence factor in a subsequent pandemic strain. This PB1-F2 protein will enhance the mortality rate of the virus by increasing the likelihood of a secondary bacterial infection, which is the primary cause of death to a patient infected with Influenza A. |*Apoptosis [MESH] |Animals [MESH] |Bacterial Infections/mortality [MESH] |Humans [MESH] |Influenza A virus/*pathogenicity [MESH] |Influenza, Human/complications/mortality/physiopathology/virology [MESH] |Macrophages, Alveolar/*physiology [MESH] |Mice [MESH] |Viral Proteins/*metabolism [MESH]The PB1-F2 protein of Influenza A virus: increasing pathogenicity by d(epmc).pdf DeepDyve Pubget Overpricing