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Effect of oral sesame oil gelatin capsules on episiotomy pain in primiparous
women: a triple-blind randomized controlled trial
#MMPMID41354976
Mehrabi Bardar M
; Omidi M
; Ahmadinezhad GS
; Arasteh S
; Salari R
; Karimi FZ
Matern Health Neonatol Perinatol
2025[Dec]; 11
(1
): 46
PMID41354976
show ga
BACKGROUND: Non-steroidal anti-inflammatory drugs are common treatments to reduce
episiotomy pain intensity. Due to the side effects of these drugs, the use of
medicinal plants has gained attention. In addition to pain reduction, the fatty
acids in sesame oil can increase the pain perception threshold and effectively
reduce episiotomy pain intensity. This study aimed to investigate the effect of
sesame oil on episiotomy pain intensity in primiparous women. METHODS: This
three-blind randomized controlled clinical trial was conducted on 88 primiparous
women at Bent Al-Hadi Hospital in Bojnord, Iran. Participants were recruited from
December 2022 to February 2024. Women meeting inclusion criteria, 2 h after
vaginal delivery, received a sesame oil gelatin capsule or placebo every 6 h for
24 h. Episiotomy pain intensity was assessed before the first intervention and
one hour after each dose using a visual pain scale. Data analysis was conducted
using SPSS software (version 25) with independent t-tests, Mann-Whitney, and
chi-square tests. A p-value of less than 0.05 was considered significant.
RESULTS: Before the first intervention, the average episiotomy pain intensity
score was 5.88?±?1.13 in the sesame oil group and 5.80?±?1.12 in the placebo
group (P?=?0.74).The average pain intensity score one hour after the first dose
(P?=?0.92) and the second dose (P?=?0.64) showed no statistical significance.
However, the average pain intensity score one hour after the third dose
(P?=?0.038) and fourth dose (P?=?0.029) in the sesame oil group was significantly
lower than the placebo group. CONCLUSION: Although at the start of the study and
after the initial two doses, there was no significant difference between the
group that received sesame oil and the group that received the placebo. However,
with continued use and after the third and fourth doses, the reduction in pain
within the group that took the sesame oil capsules was noticeably greater than in
the placebo group. This finding y indicates that the analgesic effect of sesame
oil may require time to accumulate in the body and become evident with prolonged
use.
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