Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=41341015
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Knowledge, Attitudes, and Practices Regarding Hepatitis B and Liver Cancer Among
Liver Cancer Patients and Their Families in China
#MMPMID41341015
Deng Q
; Chen Y
; He M
; Fu C
; Wu C
; Wu S
; Liu F
; Yin X
; Wu Y
; Ma K
Cancer Manag Res
2025[]; 17
(?): 2873-2891
PMID41341015
show ga
PURPOSE: This study aims to assess the knowledge, attitudes, and practices (KAP)
of liver cancer patients and their family members regarding hepatitis B and liver
cancer in hospitals in central and western China. PATIENTS AND METHODS: A
multicenter cross-sectional survey was conducted on liver cancer patients and
their families between February 2023 and August 2024. Data were collected using a
validated, self-developed questionnaire. RESULTS: A total of 810 valid
questionnaires were analyzed, with 432 (53.33%) respondents being family members.
The mean scores for knowledge, attitude, and practice were 7.19 ± 3.68, 43.71 ±
4.30, and 39.93 ± 6.06, respectively. Multivariate logistic regression identified
education (OR = 3.009 for high school/technical school; OR = 6.771 for associate
degree or above), hepatitis B diagnosis (OR = 1.530), and duration of liver
cancer diagnosis (OR=1.690) as significant predictors of knowledge scores.
Positive attitudes were linked to higher knowledge scores (OR=1.212), high
school/technical school education (OR=1.831), and a monthly per capita income of
10,000-20,000 Yuan (OR=2.964). For practices, predictors included higher
knowledge scores (OR=1.067), higher attitude scores (OR=1.241), non-disclosure of
income (OR=3.311), current alcohol consumption (OR=0.303), and diabetes
(OR=2.175). CONCLUSION: Liver cancer patients and their family members
demonstrated inadequate knowledge but relatively positive attitudes and proactive
practices regarding hepatitis B and liver cancer in hospitals in central and
western China. This knowledge-practice gap may reflect cultural norms, family
support, or public health campaigns, yet improving knowledge remains essential to
sustain positive behaviors. Targeted educational interventions should therefore
be integrated into clinical and community care. In particular, future
interventions should be tailored to address urban-rural disparities and to
actively involve family members in supporting patients. These findings provide
practical implications for enhancing health literacy, guiding policymaking, and
improving counseling strategies to strengthen disease management and prevention.
free
free
free
