Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=41170337
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
AraceaeDB: a functional genomics database of the Araceae family with a focus on
konjac glucomannan biosynthesis in Amorphophallus konjac corms
#MMPMID41170337
Chen S
; Huang Y
; Tang D
; Long Z
; Rodríguez LG
; Tian L
; Zeng M
; Wang B
; Zhao X
; Hu S
; Cao Y
Hortic Res
2025[Oct]; 12
(10
): uhaf188
PMID41170337
show ga
Amorphophallus konjac, as a significant representative of the Araceae family,
demonstrates considerable potential for applications in medicine, healthcare,
food, industry, and bioenergy due to its rich content of konjac glucomannan
(KGM). However, the synthetic pathway of KGM remains largely unclear. Although
genomic sequencing has been completed for various representative Araceae plants,
including Amorphophallus konjac, a comprehensive data platform for deep analysis
and exploration of the functions of these genes is lacking. In the current work,
genomic and transcriptomic data from multiple Araceae species were integrated,
and a database, AraceaeDB (http://www.araceaedb.com/), was constructed
specifically for analyzing and comparing gene functions in Araceae plants. The
gene functions in the database were annotated in detail, and their ortholog
groups were identified and classified into different functional modules based on
their expression patterns across various transcriptomic datasets. Multiple
functional genomics analysis tools were developed, including OrthoGroup analysis,
BLAST search, co-expression analysis, KEGG/GO enrichment analysis, and the
JBrowse visualization tool. Moreover, the database incorporates several
medicinally significant bioactive compounds traditionally important in the
Araceae family, providing target prediction capabilities for these compounds.
Furthermore, the major biosynthetic pathway of KGM has been successfully
elucidated through these database resources, and a key gene AkCSL3 has been
identified. It has been further confirmed that overexpression of AkCSL3 can
significantly increase the content of KGM, suggesting its potential crucial role
in the polymerization process of glucomannan in konjac corms.
free
free
free
