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10.1186/s12944-025-02755-8 http://scihub22266oqcxt.onion/10.1186/s12944-025-02755-8 C12551338!12551338 !41131556     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=41131556 &cmd=llinks): Failed to open stream: HTTP request failed! 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Monocyte-to-HDL ratio (MHR) as a novel biomarker: reference ranges and associations with inflammatory diseases and disease-specific mortality |pdf=|usr=}}{{41131556 }} gab.com Text Monocyte-to-HDL ratio (MHR) as a novel biomarker: reference ranges and associations with inflammatory diseases and disease-specific mortality JO: Lipids Health Dis http://www.kidney.de/pget.php?&tw=1&pmid=41131556 #FOAvip BACKGROUND: Monocyte-to-HDL Ratio (MHR) biomarker reflects monocyte-driven inflammation and HDL's anti-inflammatory properties. MHR's reference ranges and prognostic utility remain undefined. We establish normal MHR reference ranges and examine its association with inflammatory diseases and mortality. METHODS: Using NHANES data (1999-2018, 2021-2023), two sets of sex-specific MHR reference ranges were generated using two healthy adult populations (monocyte count: 6,757; monocyte percentage: 6,817). Further analyses utilized MHR by monocyte count for more straightforward interpretation. Adjusted associations between MHR and inflammatory diseases were assessed in 49,929 adults, and disease-specific mortality in 35,781. RESULTS: The 2.5th-97.5th percentiles for MHR by monocyte count were 0.175 (90% CI: 0.167-0.184) to 0.709 (90% CI: 0.690-0.727) in males and 0.135 (90% CI: 0.130-0.140) to 0.511 (90% CI: 0.503-0.520) in females, with similar trends for MHR by monocyte percentage. High MHR was most strongly associated with diabetes (aOR?=?1.76, p?<?0.001) and cardiovascular disease (aOR?=?1.69, p?<?0.001), while mortality risk was highest for kidney disease (aHR?=?3.13, p?<?0.001) and diabetes (aHR?=?2.26, p?<?0.001). CONCLUSION: MHR is a feasible and accessible biomarker of inflammation and lipid dysregulation that can be derived from routine laboratory tests and shows strong associations with cardiometabolic diseases and disease-related mortality. Twit Text FOAVip Monocyte-to-HDL ratio (MHR) as a novel biomarker: reference ranges and associations with inflammatory diseases and disease-specific mortality ????Lipids Health Dis http://www.kidney.de/pget.php?&tw=1&pmid=41131556 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41131556 #FOAvip English Wikipedia <ref>{{Cite pmid|41131556 }}</ref> Monocyte-to-HDL ratio (MHR) as a novel biomarker: reference ranges and associations with inflammatory diseases and disease-specific mortality #MMPMID41131556 Arabi A ; Abdelhamid A ; Nasrallah D ; Al-Haneedi Y ; Assami D ; Alsheikh R ; Zughaier SM Lipids Health Dis 2025[Oct]; 24 (1 ): 343 PMID41131556 show ga BACKGROUND: Monocyte-to-HDL Ratio (MHR) biomarker reflects monocyte-driven inflammation and HDL's anti-inflammatory properties. MHR's reference ranges and prognostic utility remain undefined. We establish normal MHR reference ranges and examine its association with inflammatory diseases and mortality. METHODS: Using NHANES data (1999-2018, 2021-2023), two sets of sex-specific MHR reference ranges were generated using two healthy adult populations (monocyte count: 6,757; monocyte percentage: 6,817). Further analyses utilized MHR by monocyte count for more straightforward interpretation. Adjusted associations between MHR and inflammatory diseases were assessed in 49,929 adults, and disease-specific mortality in 35,781. RESULTS: The 2.5th-97.5th percentiles for MHR by monocyte count were 0.175 (90% CI: 0.167-0.184) to 0.709 (90% CI: 0.690-0.727) in males and 0.135 (90% CI: 0.130-0.140) to 0.511 (90% CI: 0.503-0.520) in females, with similar trends for MHR by monocyte percentage. High MHR was most strongly associated with diabetes (aOR?=?1.76, p? |*Cardiovascular Diseases/mortality/blood [MESH] |*Cholesterol, HDL/blood [MESH] |*Inflammation/blood/mortality [MESH] |*Lipoproteins, HDL/blood [MESH] |*Monocytes/metabolism/pathology [MESH] |Adult [MESH] |Aged [MESH] |Biomarkers/blood [MESH] |Diabetes Mellitus/blood/mortality [MESH] |Female [MESH] |Humans [MESH] |Male [MESH] |Middle Aged [MESH] |Nutrition Surveys [MESH]Monocyte-to-HDL ratio (MHR) as a novel biomarker: reference ranges and(epmc).pdf DeepDyve Pubget Overpricing