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10.1186/s12876-025-04291-2

http://scihub22266oqcxt.onion/10.1186/s12876-025-04291-2
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suck abstract from ncbi


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pmid41131458
      BMC+Gastroenterol 2025 ; 25 (1 ): 753
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  • Association of gastroesophageal reflux disease with small intestinal bacterial overgrowth: a case-control study #MMPMID41131458
  • Hu Z ; Shan B ; Wang Y ; Yang J ; Lu L ; Wang Y ; Pang X
  • BMC Gastroenterol 2025[Oct]; 25 (1 ): 753 PMID41131458 show ga
  • OBJECTIVE: To explore the potential correlation between alterations in gut microbiota and gastroesophageal reflux disease (GERD) among patients. METHODS: A case-control study was conducted, involving 50 patients diagnosed with GERD through esophageal pressure measurement and 24-hour dynamic gastric acid monitoring, as well as 53 symptom-matched controls (SCG). All participants underwent Gastrointestinal Symptom Rating Scale (GSRS), Generalized Anxiety Disorder 7-item scale (GAD-7), and Pittsburgh Sleep Quality Index (PSQI) assessments. Methane (CH(4)) and hydrogen (H(2)) breath tests were conducted to collect essential clinical data for both groups. Finally, the relationship between small intestinal bacterial overgrowth (SIBO) and GERD was analyzed using Spearman correlation analysis. RESULTS: In the GERD group, GSRS, anxiety rate, and PSQI were all increased (p?
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