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2025 ; 25
(1
): 595
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English Wikipedia
StrabNet-CQ: an integrated deep learning framework for automated strabismus
classification and quantification using ocular landmark detection
#MMPMID41131496
Garg S
; Sunkarapalli A
; Ghosh D
; Kaur S
; Sukhija J
BMC Ophthalmol
2025[Oct]; 25
(1
): 595
PMID41131496
show ga
BACKGROUND: Strabismus is a common ocular misalignment that can impair binocular
vision if untreated. Conventional diagnosis and treatment rely on clinical prism
diopter (PD) readings, which quantify deviation along with base direction.
However, these values are coarse, manual, and subject to inter-clinician
variability. METHODS: We present the development and results of StrabNet-CQ
(Strabismus Network for Classification and Quantification), a newly developed
deep learning-based framework for automated strabismus classification and
quantification. Six hundred eye images, with and without strabismus, were
analyzed by the model. A YOLOv8 model performs classification into normal and
abnormal as well as subsequent classification (normal, esotropia, exotropia,
hypertropia, hypotropia), with refined classification via ResNet101 on segmented
eye regions from the images. Ocular landmarks are detected using ResNet18, from
which horizontal and vertical deviation indices and angular deviation are
computed. RESULTS: The system achieved 94% accuracy in strabismus detection and
90% in strabismus classification, with high sensitivity for normal (0.91-1.00),
esotropia (0.89), and hypotropia (0.90). The derived parameters show a good
correlation with manual PD values(r?=?0.733) that can be utilized for
quantification of strabismus. CONCLUSION: StrabNet-CQ supports objective
diagnosis and holds promise for deployment in clinical settings for strabismus
detection as well as quantification.