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10.1186/s12936-025-05450-2

http://scihub22266oqcxt.onion/10.1186/s12936-025-05450-2
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suck abstract from ncbi


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pmid41131552
      Malar+J 2025 ; 24 (1 ): 360
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  • The usual suspect-malaria? Diagnostic challenges in post-artesunate delayed haemolysis: a clinical laboratory perspective through a case report #MMPMID41131552
  • Molnar E ; Cabral PM ; Portal F ; Guimarães AR ; Santos L ; Guimarães JT
  • Malar J 2025[Oct]; 24 (1 ): 360 PMID41131552 show ga
  • Malaria, a potentially fatal infectious disease, remains a significant global health concern, mainly in tropical regions. In Europe, its incidence is currently low and predominantly travel-related. Thus, a timely diagnosis requires healthcare teams to consider malaria in their differential diagnoses and obtain a thorough travel history. In medical laboratories, despite the present low case numbers, professionals must maintain a high diagnostic proficiency through continuous training and adherence to quality assurance programmes. First-line anti-malarial treatment with artemisinin derivatives is highly effective when implemented in a timely manner. However, as a consequence of their efficacy, a predictable haemolytic phenomenon may occur in some cases, which may be difficult to distinguish from manifestations of the disease itself. This mini review examines a case of travel-associated malaria to highlight diagnostic challenges from a medical laboratory perspective, with a particular focus on post-artesunate delayed haemolysis (PADH), a rare but potentially severe complication of malaria treatment.
  • |*Antimalarials/adverse effects/therapeutic use/administration & dosage [MESH]
  • |*Artemisinins/adverse effects/therapeutic use [MESH]
  • |*Artesunate/adverse effects [MESH]
  • |*Hemolysis/drug effects [MESH]
  • |*Malaria/drug therapy/diagnosis [MESH]
  • |Humans [MESH]
  • |Male [MESH]


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