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10.1186/s12891-025-09184-9

http://scihub22266oqcxt.onion/10.1186/s12891-025-09184-9
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suck abstract from ncbi


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pmid41131492
      BMC+Musculoskelet+Disord 2025 ; 26 (1 ): 988
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  • Exploring feasibility of health-related quality of life assessments and pain diaries in patients undergoing prehabilitation before total knee arthroplasty: a pilot study #MMPMID41131492
  • Gränicher P ; Kocher M ; de Bie R ; Swanenburg J ; Scherr J
  • BMC Musculoskelet Disord 2025[Oct]; 26 (1 ): 988 PMID41131492 show ga
  • BACKGROUND: Prehabilitation prior to total knee arthroplasty (TKA) may mitigate deterioration in health-related quality of life (HRQOL) during the preoperative period and support recovery after surgery. However, little is known about the feasibility of systematically monitoring HRQOL and pain through patient-reported outcome measures (PROMs) in this context. This pilot study aimed to evaluate the feasibility of using validated HRQOL questionnaires and daily pain diaries during a prehabilitation programme for patients awaiting (TKA) and up to 12 weeks postoperatively. METHODS: Twenty patients (mean age 73?±?6 years) scheduled for primary unilateral TKA were randomly assigned to an intervention group (IG) or control group (CG). The IG participated in a 4- to 8-week individualised prehabilitation programme involving exercise and education. Feasibility was assessed through the completion rates of daily pain diaries and three HRQOL questionnaires (EQ-5D-5 L, SF-12 and KOOS KRQOL) collected at baseline, preoperatively, and at 6- and 12-weeks postoperatively. RESULTS: HRQOL questionnaires demonstrated high completion rates across both groups (90%). In contrast, adherence to paper-based pain diaries was suboptimal and notably low (CG: 58%; IG: 47%), falling below the threshold for meaningful analysis. Consequently, pain trajectory over time could not be reliably assessed. No significant group-by-time interaction effects were observed for any HRQOL measure: EQ-5D-5 L (p?=?0.67; F?=?0.51), KOOS KRQOL (p?=?0.72; F?=?0.64), SF-12 PCS (p?=?0.06; F?=?0.50) and MCS (p?=?0.36; F?=?0.10). CONCLUSION: This pilot study confirms the feasibility and acceptability of HRQOL questionnaires in older patients undergoing prehabilitation before TKA. However, the low diary completion rates highlight the need for alternative pain-monitoring-approaches - such as electronic formats - to improve data quality in future trials. Preliminary findings suggest potential benefits of prehabilitation, warranting further investigation in larger studies. TRIAL REGISTRATION: ClinicalTrials.gov Identifier; NCT05314985. Registered 20 July 2021. BASEC-Nr. 2020-03060.
  • |*Arthroplasty, Replacement, Knee/adverse effects/rehabilitation [MESH]
  • |*Pain Measurement/methods [MESH]
  • |*Patient Reported Outcome Measures [MESH]
  • |*Preoperative Care/methods [MESH]
  • |*Preoperative Exercise [MESH]
  • |*Quality of Life [MESH]
  • |Aged [MESH]
  • |Aged, 80 and over [MESH]
  • |Feasibility Studies [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Pilot Projects [MESH]


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