Comparison of the analgesic efficacy of dexketoprofen trometamol and paracetamol
with naproxen sodium and codeine phosphate combinations in acute toothache
#MMPMID41107344
Do?ru ?
; Ci?erim L
Sci Rep
2025[Oct]; 15
(1
): 36381
PMID41107344
show ga
The aim of this study was to evaluate the efficacy of naproxen sodium?+?codeine
phosphate and dexketoprofen trometamol?+?paracetamol combinations in the
treatment of acute dental pain during the preoperative period. Patients with
complaints of acute pericoronitis caused by a semi-erupted lower impacted third
molar were included in the study. Patients were randomly divided into two groups,
naproxen sodium?+?codeine phosphate (550/30 mg) in group A and dexketoprofen
trometamol?+?paracetamol (25/300 mg) in group B, and pain was assessed by VAS.
The collected data were statistically analysed and interpreted using SPSS. The
Friedman test (a non-parametric test) was used to analyse data within groups. The
independent groups t-test and Mann-Whitney U-test were used to analyse data
between groups. Of the 62 patients included in the study, 51 (82.3%) were female
and 11 (17.7%) were male, with a mean age of 22.94 years. As a result of the
7-day evaluation, the VAS average in group A decreased from 7.61 to 1.26,
representing an 83.44% decrease, while in group B, it decreased from 7.19 to
0.61, representing an 91.52% decrease. When the VAS averages of groups A and B
were compared over time, statistically significant differences were only found
between the values on day 7 (p?
free
free
free
