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10.1186/s12876-025-04192-4 http://scihub22266oqcxt.onion/10.1186/s12876-025-04192-4 C12533318!12533318 !41102651     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 286.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 286.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 286.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 320.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 320.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 320.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 320.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 387.59999999999997 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 387.59999999999997 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\41102651 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMC+Gastroenterol 2025 ; 25 (1 ): 738 Nephropedia Template TP {{tp|p=41102651 |t=2025. Efficacy of hydration combined with rectal non-steroidal anti-inflammatory drugs (NSAIDs) versus NSAIDs alone for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis of randomized controlled trials |pdf=|usr=}}{{41102651 }} gab.com Text Efficacy of hydration combined with rectal non-steroidal anti-inflammatory drugs (NSAIDs) versus NSAIDs alone for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis of randomized controlled trials JO: BMC Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=41102651 #FOAvip BACKGROUND: The most prevalent complication of endoscopic retrograde cholangiopancreatography (ERCP) is post-ERCP acute pancreatitis (PEP). Both hydration and rectal non-steroidal anti-inflammatory drugs (NSAIDs) can effectively prevent PEP; however, there is currently no consensus on whether combination therapy is more effective than either intervention alone. METHODS: The PubMed/Medline, Web of Science, Embase and Cochrane Library (last updated in October 2024) were systematically searched to identify and screen potentially eligible studies, from which relevant data were extracted, Review Manager 5.3 was used for meta-analysis to determine the preventive utility of hydration?+?rectal NSAIDs for PEP. RESULTS: Five studies comprising 1344 patients were included in the meta-analysis. Patients were divided into 2 groups (hydration?+?NSAIDs [n=654] and NSAIDs alone [n=690], a total of 107 patients experienced PEP (hydration?+?NSAIDs [n=40] and NSAIDs alone [n=67]). Results of meta-analysis revealed no significant difference in the incidence of PEP between patients receiving rectal NSAIDs?+?hydration versus rectal NSAIDs alone (odds ratio [OR] 0.57, 95% confidence interval [CI] 0.25-1.30; P?=?0.18). CONCLUSION: Compared with rectal NSAIDs alone, the combination of hydration and rectal NSAIDs does not appear to have a significant synergistic effect in the prevention of PEP. However, considering their distinct mechanisms of action and the observed reduction in PEP incidence with combined use, we believe that this approach still holds considerable clinical relevance. Further large-scale studies are needed to validate these findings. Twit Text FOAVip Efficacy of hydration combined with rectal non-steroidal anti-inflammatory drugs (NSAIDs) versus NSAIDs alone for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis of randomized controlled trials ????BMC Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=41102651 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41102651 #FOAvip English Wikipedia <ref>{{Cite pmid|41102651 }}</ref> Efficacy of hydration combined with rectal non-steroidal anti-inflammatory drugs (NSAIDs) versus NSAIDs alone for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis of randomized controlled trials #MMPMID41102651 Li H ; Miao C ; Fang W ; Deng Y ; Li X ; Du T ; Tian H BMC Gastroenterol 2025[Oct]; 25 (1 ): 738 PMID41102651 show ga BACKGROUND: The most prevalent complication of endoscopic retrograde cholangiopancreatography (ERCP) is post-ERCP acute pancreatitis (PEP). Both hydration and rectal non-steroidal anti-inflammatory drugs (NSAIDs) can effectively prevent PEP; however, there is currently no consensus on whether combination therapy is more effective than either intervention alone. METHODS: The PubMed/Medline, Web of Science, Embase and Cochrane Library (last updated in October 2024) were systematically searched to identify and screen potentially eligible studies, from which relevant data were extracted, Review Manager 5.3 was used for meta-analysis to determine the preventive utility of hydration?+?rectal NSAIDs for PEP. RESULTS: Five studies comprising 1344 patients were included in the meta-analysis. Patients were divided into 2 groups (hydration?+?NSAIDs [n=654] and NSAIDs alone [n=690], a total of 107 patients experienced PEP (hydration?+?NSAIDs [n=40] and NSAIDs alone [n=67]). Results of meta-analysis revealed no significant difference in the incidence of PEP between patients receiving rectal NSAIDs?+?hydration versus rectal NSAIDs alone (odds ratio [OR] 0.57, 95% confidence interval [CI] 0.25-1.30; P?=?0.18). CONCLUSION: Compared with rectal NSAIDs alone, the combination of hydration and rectal NSAIDs does not appear to have a significant synergistic effect in the prevention of PEP. However, considering their distinct mechanisms of action and the observed reduction in PEP incidence with combined use, we believe that this approach still holds considerable clinical relevance. Further large-scale studies are needed to validate these findings. |*Anti-Inflammatory Agents, Non-Steroidal/administration & dosage/therapeutic use [MESH] |*Cholangiopancreatography, Endoscopic Retrograde/adverse effects [MESH] |*Fluid Therapy/methods [MESH] |*Pancreatitis/prevention & control/etiology [MESH] |Administration, Rectal [MESH] |Combined Modality Therapy [MESH] |Humans [MESH]Efficacy of hydration combined with rectal non-steroidal anti-inflamma(epmc).pdf DeepDyve Pubget Overpricing