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10.1136/bmjopen-2025-101122 http://scihub22266oqcxt.onion/10.1136/bmjopen-2025-101122 C12530432!12530432 !41101963     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 280.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 280.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\41101963 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMJ+Open 2025 ; 15 (10 ): e101122 Nephropedia Template TP {{tp|p=41101963 |t=2025. Prevalence and impact of comorbid PTSD, c-PTSD and EUPD on symptom severity in functional neurological disorder: protocol for a systematic review and meta-analysis |pdf=|usr=}}{{41101963 }} gab.com Text Prevalence and impact of comorbid PTSD, c-PTSD and EUPD on symptom severity in functional neurological disorder: protocol for a systematic review and meta-analysis JO: BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=41101963 #FOAvip INTRODUCTION: Previous trauma and adverse life experiences have been hypothesised to be aetiological factors for functional neurological disorder (FND) leading to the hypothesis of a 'trauma-subtype' of FND. Individuals who have experienced prior abuse are more likely to develop FND than healthy controls. Post-traumatic stress disorder (PTSD) and personality disorders have been described to be comorbid with FND at varying prevalence rates. Complex PTSD (c-PTSD) and emotionally unstable personality disorder (EUPD) have clinical similarities with PTSD and trauma is a common aetiological factor in the development of all three conditions. There is some research exploring the resemblance of personality traits in populations diagnosed with FND and EUPD compared with controls. However, it remains unclear what the current prevalence rates are of PTSD, c-PTSD and EUPD in populations diagnosed with FND. Understanding the overlap between these trauma-based comorbid psychiatric diagnoses with FND will hopefully inform better and more comprehensive trauma-informed treatment strategies. The aims of the systematic review are therefore to (1) establish the prevalence of PTSD, c-PTSD and EUPD in adults diagnosed with FND and (2) compare core FND symptom severity between adults with FND alone and those with comorbid PTSD, c-PTSD and EUPD. METHODS AND ANALYSIS: This systematic review will assess the prevalence of PTSD, c-PTSD and EUPD in FND patients aged over 18, diagnosed using standardised questionnaires or clinical interviews as per international diagnostic criteria. Studies will be identified through comprehensive searches of databases including PsycINFO, PsycARTICLES, CINAHL, MEDLINE, EMBASE, Web of Science and Scopus, from May 1990 to May 2025. The review aims to estimate the prevalence of these conditions in FND, with findings presented as a narrative description discussing contributing factors, and a meta-analysis considered if heterogeneity is suitable. ETHICS AND DISSEMINATION: Ethical approval is not required since only data from existing studies will be used and no original data will be collected. Results will be disseminated at national and international academic conferences and in peer-reviewed publications. Any deviations from this protocol will be recorded and explained in the final report and updated on PROSPERO. PROSPERO REGISTRATION NUMBER: CRD42024599112. Twit Text FOAVip Prevalence and impact of comorbid PTSD, c-PTSD and EUPD on symptom severity in functional neurological disorder: protocol for a systematic review and meta-analysis ????BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=41101963 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41101963 #FOAvip English Wikipedia <ref>{{Cite pmid|41101963 }}</ref> Prevalence and impact of comorbid PTSD, c-PTSD and EUPD on symptom severity in functional neurological disorder: protocol for a systematic review and meta-analysis #MMPMID41101963 Davies S ; Rafi D ; Rifkin-Zybutz R ; Heyland S ; Jadhakhan F BMJ Open 2025[Oct]; 15 (10 ): e101122 PMID41101963 show ga INTRODUCTION: Previous trauma and adverse life experiences have been hypothesised to be aetiological factors for functional neurological disorder (FND) leading to the hypothesis of a 'trauma-subtype' of FND. Individuals who have experienced prior abuse are more likely to develop FND than healthy controls. Post-traumatic stress disorder (PTSD) and personality disorders have been described to be comorbid with FND at varying prevalence rates. Complex PTSD (c-PTSD) and emotionally unstable personality disorder (EUPD) have clinical similarities with PTSD and trauma is a common aetiological factor in the development of all three conditions. There is some research exploring the resemblance of personality traits in populations diagnosed with FND and EUPD compared with controls. However, it remains unclear what the current prevalence rates are of PTSD, c-PTSD and EUPD in populations diagnosed with FND. Understanding the overlap between these trauma-based comorbid psychiatric diagnoses with FND will hopefully inform better and more comprehensive trauma-informed treatment strategies. The aims of the systematic review are therefore to (1) establish the prevalence of PTSD, c-PTSD and EUPD in adults diagnosed with FND and (2) compare core FND symptom severity between adults with FND alone and those with comorbid PTSD, c-PTSD and EUPD. METHODS AND ANALYSIS: This systematic review will assess the prevalence of PTSD, c-PTSD and EUPD in FND patients aged over 18, diagnosed using standardised questionnaires or clinical interviews as per international diagnostic criteria. Studies will be identified through comprehensive searches of databases including PsycINFO, PsycARTICLES, CINAHL, MEDLINE, EMBASE, Web of Science and Scopus, from May 1990 to May 2025. The review aims to estimate the prevalence of these conditions in FND, with findings presented as a narrative description discussing contributing factors, and a meta-analysis considered if heterogeneity is suitable. ETHICS AND DISSEMINATION: Ethical approval is not required since only data from existing studies will be used and no original data will be collected. Results will be disseminated at national and international academic conferences and in peer-reviewed publications. Any deviations from this protocol will be recorded and explained in the final report and updated on PROSPERO. PROSPERO REGISTRATION NUMBER: CRD42024599112. |*Nervous System Diseases/epidemiology [MESH] |*Personality Disorders/epidemiology [MESH] |*Stress Disorders, Post-Traumatic/epidemiology [MESH] |Comorbidity [MESH] |Humans [MESH] |Meta-Analysis as Topic [MESH] |Prevalence [MESH] |Research Design [MESH] |Severity of Illness Index [MESH]Prevalence and impact of comorbid PTSD, c-PTSD and EUPD on symptom sev(epmc).pdf DeepDyve Pubget Overpricing