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10.1136/bmjpo-2025-003679 http://scihub22266oqcxt.onion/10.1136/bmjpo-2025-003679 C12530372!12530372 !41101785     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\41101785 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMJ+Paediatr+Open 2025 ; 9 (1 ): ä Nephropedia Template TP {{tp|p=41101785 |t=2025. Leak during term neonatal CPAP stabilisation: does resuscitation device design affect delivered PEEP - a bench study |pdf=|usr=}}{{41101785 }} gab.com Text Leak during term neonatal CPAP stabilisation: does resuscitation device design affect delivered PEEP - a bench study JO: BMJ Paediatr Open http://www.kidney.de/pget.php?&tw=1&pmid=41101785 #FOAvip BACKGROUND: Mask leak is common during newborn resuscitation, impacting delivered ventilation. Less is known about the effect of leak during assisted spontaneous breathing with continuous positive airway pressure (CPAP). AIM: Compare CPAP performance in the presence of leak of two T-piece resuscitation devices, with differing design-imposed resistances: high resistance Neopuff and low resistance rPAP. METHODS: Devices were tested on a term dynamic lung model (compliance 1.0?mL/cmH(2)O, tidal volume (VT) 23?mL) at three incremental leak levels and set positive end expiratory pressure (PEEP) 5 cmH(2)O, 7 cmH(2)O and 9 cmH(2)O. Continuous leaks were generated by differing-length tubes open to atmosphere. Measured parameters were mean pressure, fluctuations around set pressure (?P), VT and leak flow. RESULTS: 2437 breaths were analysed (1216 rPAP, 1221 Neopuff). Leak reduced PEEP, with the largest reduction at the highest leak and 9 cmH(2)O set PEEP (Neopuff 2.6 cmH(2)O vs rPAP 7.0 cmH(2)O). Higher delivered PEEP was associated with higher leak flows (Neopuff 4.4 L/min vs rPAP 8.2?L/min, 9 cmH(2)O set PEEP). VT reduced with Neopuff compared with rPAP (Neopuff 18 mL vs rPAP 23.2?mL, no leak, 9 cmH(2)O set PEEP) and was affected by delivered PEEP. CONCLUSION: The delivered support differed between devices in the presence of leaks. rPAP maintained pressures closer to the set PEEP value at all leak levels, and higher leak flows were seen with the maintained distending pressure. Neopuff's higher resistance led to reductions in VT that were more pronounced at low leak levels. Twit Text FOAVip Leak during term neonatal CPAP stabilisation: does resuscitation device design affect delivered PEEP - a bench study ????BMJ Paediatr Open http://www.kidney.de/pget.php?&tw=1&pmid=41101785 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41101785 #FOAvip English Wikipedia <ref>{{Cite pmid|41101785 }}</ref> Leak during term neonatal CPAP stabilisation: does resuscitation device design affect delivered PEEP - a bench study #MMPMID41101785 Gruber V ; Morakeas S ; Hinder M ; Drevhammar T ; Dronavalli M ; Tracy MB BMJ Paediatr Open 2025[Oct]; 9 (1 ): ä PMID41101785 show ga BACKGROUND: Mask leak is common during newborn resuscitation, impacting delivered ventilation. Less is known about the effect of leak during assisted spontaneous breathing with continuous positive airway pressure (CPAP). AIM: Compare CPAP performance in the presence of leak of two T-piece resuscitation devices, with differing design-imposed resistances: high resistance Neopuff and low resistance rPAP. METHODS: Devices were tested on a term dynamic lung model (compliance 1.0?mL/cmH(2)O, tidal volume (VT) 23?mL) at three incremental leak levels and set positive end expiratory pressure (PEEP) 5 cmH(2)O, 7 cmH(2)O and 9 cmH(2)O. Continuous leaks were generated by differing-length tubes open to atmosphere. Measured parameters were mean pressure, fluctuations around set pressure (?P), VT and leak flow. RESULTS: 2437 breaths were analysed (1216 rPAP, 1221 Neopuff). Leak reduced PEEP, with the largest reduction at the highest leak and 9 cmH(2)O set PEEP (Neopuff 2.6 cmH(2)O vs rPAP 7.0 cmH(2)O). Higher delivered PEEP was associated with higher leak flows (Neopuff 4.4 L/min vs rPAP 8.2?L/min, 9 cmH(2)O set PEEP). VT reduced with Neopuff compared with rPAP (Neopuff 18 mL vs rPAP 23.2?mL, no leak, 9 cmH(2)O set PEEP) and was affected by delivered PEEP. CONCLUSION: The delivered support differed between devices in the presence of leaks. rPAP maintained pressures closer to the set PEEP value at all leak levels, and higher leak flows were seen with the maintained distending pressure. Neopuff's higher resistance led to reductions in VT that were more pronounced at low leak levels. |*Continuous Positive Airway Pressure/instrumentation [MESH] |*Masks [MESH] |*Positive-Pressure Respiration/instrumentation [MESH] |*Resuscitation/instrumentation [MESH] |Equipment Design [MESH] |Equipment Failure [MESH] |Humans [MESH] |Infant, Newborn [MESH]Leak during term neonatal CPAP stabilisation: does resuscitation devic(epmc).pdf DeepDyve Pubget Overpricing