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2025 ; 15
(10
): e108778
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Patient perspectives on access to oncology innovations: protocol for a systematic
meta-aggregation review
#MMPMID41101962
Julliot-Delval A
; Teixeira M
; Cartron E
BMJ Open
2025[Oct]; 15
(10
): e108778
PMID41101962
show ga
INTRODUCTION: Healthcare innovation in oncology has accelerated in recent years,
with the development of targeted therapies, digital tools and novel care
pathways. While these advances promise improved outcomes, concerns remain about
unequal access across patient populations. Patient perspectives on access to
innovation remain underexplored, yet may offer valuable insights to support more
equitable and patient-centred implementation strategies. OBJECTIVES: This
meta-aggregation study aims to explore how adult patients with cancer perceive
their access to healthcare innovations. A secondary objective is to identify the
barriers, facilitators and contextual factors that influence this access, as well
as patients' understandings or definitions of innovation, when available. METHOD
AND ANALYSIS: A systematic meta-aggregation review will be conducted according to
the Joanna Briggs Institute (JBI) methodology. Full-text, peer-reviewed articles
reporting qualitative studies of patients' experiences with innovations in
oncology will be included. Studies will be identified through searches in PubMed,
CINAHL, PsycINFO and Cairn.info, with no date restrictions. Articles in English
and French will be considered. Two independent reviewers will screen and extract
data and assess methodological quality using the JBI checklist. Synthesis will
follow the JBI three-phase approach. Confidence in the evidence will be assessed
using the GRADE-CERQual (Confidence in the Evidence from Reviews of Qualitative
research) tool. The Preferred Reporting Items for Systematic Reviews and
Meta-Analyses (PRISMA) 2020 reporting guidelines will be followed. ETHICS AND
DISSEMINATION: Ethical approval is not required for this study, as it is based on
previously published data. The findings will be disseminated through publication
in peer-reviewed journals and presentations at scientific conferences. PROSPERO
REGISTRATION NUMBER: CRD420251046315.