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10.1155/sci5/8015648 http://scihub22266oqcxt.onion/10.1155/sci5/8015648 C12206570!12206570 !40590050     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40590050 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Scientifica+(Cairo) 2025 ; 2025 (ä): 8015648 Nephropedia Template TP {{tp|p=40590050 |t=2025. Bioactivity Profiling of Chemically Characterized Extract of Saudi Jackfruit (Artocarpus heterophyllus) Using In Vitro and In Silico Approaches |pdf=|usr=}}{{40590050 }} gab.com Text Bioactivity Profiling of Chemically Characterized Extract of Saudi Jackfruit (Artocarpus heterophyllus) Using In Vitro and In Silico Approaches JO: Scientifica (Cairo) http://www.kidney.de/pget.php?&tw=1&pmid=40590050 #FOAvip Artocarpus heterophyllus, also known as jackfruit, is recently introduced for cultivation in Saudi Arabia. In this study, the ethanolic extract of Artocarpus heterophyllus fruits (EAHF) was explored for its chemical and pharmacological properties. The EAHF was revealed with total phenolic contents (115.5?±?5?mg GA.Eq.gm(-1) DE), total flavonoid contents (77?±?2.22?mg QU.Eq.gm(-1) DE), and total tannin contents (59.33?±?1.66?mg TA.Eq.gm(-1) DE), while 81 phytocompounds were identified by the GC-MS analysis. The extract was found with maximum antioxidant activity in the FRAP method. EAHF showed significant thrombolytic (85.51%) and hemolytic (1.01%) activities. EAHF showed strong enzyme inhibition, against urease (95.65%), tyrosinase(71.01%), and ?-amylase(28.17%). The extract showed cytotoxicity potential against breast cancer cell lines (MCF-7 and MDA-MB-231) in a concentration and time-dependent manner. Furthermore, selected compounds from the GC-MS profile were tested for in silico toxicity, ADMET, and molecular docking study to analyze the interactions between compounds and selected enzymes. Overall, the findings of the study suggest that the EAHF has pharmacological potential and could be a suitable therapeutic alternative for various common diseases. However, further, in vivo toxicological and pharmacological investigations are recommended on this extract. Twit Text FOAVip Bioactivity Profiling of Chemically Characterized Extract of Saudi Jackfruit (Artocarpus heterophyllus) Using In Vitro and In Silico Approaches ????Scientifica (Cairo) http://www.kidney.de/pget.php?&tw=1&pmid=40590050 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40590050 #FOAvip English Wikipedia <ref>{{Cite pmid|40590050 }}</ref> Bioactivity Profiling of Chemically Characterized Extract of Saudi Jackfruit (Artocarpus heterophyllus) Using In Vitro and In Silico Approaches #MMPMID40590050 Aati HY ; Al-Arifi R ; Ovatlarnporn C ; Rauf A ; Basit A ; Rao H ; Batool M ; Khan KUR Scientifica (Cairo) 2025[]; 2025 (ä): 8015648 PMID40590050 show ga Artocarpus heterophyllus, also known as jackfruit, is recently introduced for cultivation in Saudi Arabia. In this study, the ethanolic extract of Artocarpus heterophyllus fruits (EAHF) was explored for its chemical and pharmacological properties. The EAHF was revealed with total phenolic contents (115.5?±?5?mg GA.Eq.gm(-1) DE), total flavonoid contents (77?±?2.22?mg QU.Eq.gm(-1) DE), and total tannin contents (59.33?±?1.66?mg TA.Eq.gm(-1) DE), while 81 phytocompounds were identified by the GC-MS analysis. The extract was found with maximum antioxidant activity in the FRAP method. EAHF showed significant thrombolytic (85.51%) and hemolytic (1.01%) activities. EAHF showed strong enzyme inhibition, against urease (95.65%), tyrosinase(71.01%), and ?-amylase(28.17%). The extract showed cytotoxicity potential against breast cancer cell lines (MCF-7 and MDA-MB-231) in a concentration and time-dependent manner. Furthermore, selected compounds from the GC-MS profile were tested for in silico toxicity, ADMET, and molecular docking study to analyze the interactions between compounds and selected enzymes. Overall, the findings of the study suggest that the EAHF has pharmacological potential and could be a suitable therapeutic alternative for various common diseases. However, further, in vivo toxicological and pharmacological investigations are recommended on this extract. äBioactivity Profiling of Chemically Characterized Extract of Saudi Jac(epmc).pdf DeepDyve Pubget Overpricing