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10.2147/IMCRJ.S527975

http://scihub22266oqcxt.onion/10.2147/IMCRJ.S527975
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suck abstract from ncbi


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pmid40585966
      Int+Med+Case+Rep+J 2025 ; 18 (ä): 741-746
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  • Full-Thickness Macular Hole Formation After Intravitreal Faricimab Injection for Polypoidal Choroidal Vasculopathy #MMPMID40585966
  • Tavonvunchai F ; Chanwimol K
  • Int Med Case Rep J 2025[]; 18 (ä): 741-746 PMID40585966 show ga
  • PURPOSE: To report a case of an Asian man with idiopathic polypoidal choroidal vasculopathy (PCV) who developed a full-thickness macular hole (FTMH) following treatment with intravitreal faricimab, which resolved after vitreoretinal surgery. PATIENTS AND METHODS: A 63-year-old man with idiopathic PCV was treated with intravitreal faricimab. Although pigment epithelial detachment (PED) decreased, he developed cystoid macular edema with vitreomacular traction (VMT), which progressed to a FTMH. RESULTS: Pars plana vitrectomy and internal limiting membrane peeling successfully treated the FTMH. One year after the procedure, the macular hole remains closed, and the PCV was inactive. CONCLUSION: Various mechanisms may have contributed to the exacerbation of the preexisting VMT and PED, which finally resulted in the development of a FTMH. Careful attention should be paid to changes in the vitreomacular interface and posterior vitreous detachment before performing intravitreal anti-vascular endothelial growth factor treatment. Nevertheless, FTMHs can be successfully treated with prompt vitreoretinal surgery.
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