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2025 ; 2025
(6
): rjaf426
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Case report and literature review of gallbladder paraganglioma in patient with
inflammatory bowel disease
#MMPMID40585934
Dominkovic M
; Allan L
; Pleass H
J Surg Case Rep
2025[Jun]; 2025
(6
): rjaf426
PMID40585934
show ga
Primary paraganglioma of the gallbladder is an extremely rare pathology. Only 21
cases have been reported in the literature, and we present the first reported
case of gallbladder paraganglioma in a patient with inflammatory bowel disease
and primary sclerosing cholangitis. A 54-year-old lady with history of chronic
right upper quadrant pain on a background of inflammatory bowel disease and
primary sclerosing cholangitis underwent laparoscopic cholecystectomy due to
gallbladder polyps and gallbladder wall irregularity on surveillance imaging. Her
histopathology incidentally noted gallbladder paraganglioma. Due to their
scarcity, there is no consensus on management and follow-up of gallbladder
paraganglioma. All previously reported cases have been thus far benign and
adequately treated with cholecystectomy, however, intra-abdominal extra-adrenal
paragangliomas have malignant and metastatic potential hence we would advocate
for surveillance.