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10.1002/fsn3.70518 http://scihub22266oqcxt.onion/10.1002/fsn3.70518 C12203404!12203404 !40585503     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40585503 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Food+Sci+Nutr 2025 ; 13 (7 ): e70518 Nephropedia Template TP {{tp|p=40585503 |t=2025. Chemical Characterization, Antidiabetic and Antioxidant Potential of Allium cepa Peels Silver Nanoparticles Against Alloxan Induced Diabetes in Rabbits |pdf=|usr=}}{{40585503 }} gab.com Text Chemical Characterization, Antidiabetic and Antioxidant Potential of Allium cepa Peels Silver Nanoparticles Against Alloxan Induced Diabetes in Rabbits JO: Food Sci Nutr http://www.kidney.de/pget.php?&tw=1&pmid=40585503 #FOAvip Diabetes is one of the major causes of death worldwide. Onion peels have antioxidant and antidiabetic activities due to the presence of flavonoids and phenolic compounds. In current research, the antidiabetic potential of a herbal-based silver nanodrug synthesized using aqueous extract of Allium cepa peels was studied against Alloxan-induced diabetes in rabbits. The green synthesized reduced silver nanoparticles (AgNPs) and aqueous extract were characterized using X-ray diffraction analysis (XRD) and liquid chromatography mass spectrometry (LCMS-MS) analysis. After the acclimation period, the rabbits were divided into nine groups of 5 rabbits each (n?=?5). Experimental animals were injected with a single dose of Alloxan monohydrate (160?mg/mL per kg BW) and then orally treated with aqueous extract of A. cepa peels and AgNPs at three dose concentrations (100, 200, 300?mg/mL per kg BW) for 20?days. Serum levels of blood sugar, renal function tests, lipid profile, and oxidative stress markers were determined photometrically. Results from mass spectral analysis revealed that quercetin and vanillic acid are the major phenolic compounds. XRD analysis confirmed the stabilization and shape of green synthesized AgNPs. Results from in vivo studies indicated that treatment with aqueous extract of A. cepa peels and AgNPs attenuated the Alloxan-induced diabetes in a dose-dependent manner, as demonstrated by a decrease in blood sugar, triglycerides, urea, creatinine, and cholesterol to 100?±?0.8, 57.66?±?0.8, 38?±?0.8, 1.11?±?0.08, 40?±?0.00?mg/dL, respectively, in rabbits administered with 300?mg/mL per kg BW AgNPs. The levels of oxidative stress markers (CAT, SOD, and GPx) in blood, that is, 3.6?±?0.08, 6.0?±?0.08, 918?±?2.0?IU/mL, respectively, were also increased in rabbits administered with 300?mg/mL per kg BW AgNPs. Our results conclude that synthesized AgNPs using aqueous extract of A. cepa peels have a protective effect against Alloxan-induced diabetes. Twit Text FOAVip Chemical Characterization, Antidiabetic and Antioxidant Potential of Allium cepa Peels Silver Nanoparticles Against Alloxan Induced Diabetes in Rabbits ????Food Sci Nutr http://www.kidney.de/pget.php?&tw=1&pmid=40585503 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40585503 #FOAvip English Wikipedia <ref>{{Cite pmid|40585503 }}</ref> Chemical Characterization, Antidiabetic and Antioxidant Potential of Allium cepa Peels Silver Nanoparticles Against Alloxan Induced Diabetes in Rabbits #MMPMID40585503 Batool S ; Abbas M ; Ashraf S ; Rafique MK ; Mumtaz A ; Hussain T ; Riaz M ; Rasool G ; Ayub MA ; Akter QS Food Sci Nutr 2025[Jul]; 13 (7 ): e70518 PMID40585503 show ga Diabetes is one of the major causes of death worldwide. Onion peels have antioxidant and antidiabetic activities due to the presence of flavonoids and phenolic compounds. In current research, the antidiabetic potential of a herbal-based silver nanodrug synthesized using aqueous extract of Allium cepa peels was studied against Alloxan-induced diabetes in rabbits. The green synthesized reduced silver nanoparticles (AgNPs) and aqueous extract were characterized using X-ray diffraction analysis (XRD) and liquid chromatography mass spectrometry (LCMS-MS) analysis. After the acclimation period, the rabbits were divided into nine groups of 5 rabbits each (n?=?5). Experimental animals were injected with a single dose of Alloxan monohydrate (160?mg/mL per kg BW) and then orally treated with aqueous extract of A. cepa peels and AgNPs at three dose concentrations (100, 200, 300?mg/mL per kg BW) for 20?days. Serum levels of blood sugar, renal function tests, lipid profile, and oxidative stress markers were determined photometrically. Results from mass spectral analysis revealed that quercetin and vanillic acid are the major phenolic compounds. XRD analysis confirmed the stabilization and shape of green synthesized AgNPs. Results from in vivo studies indicated that treatment with aqueous extract of A. cepa peels and AgNPs attenuated the Alloxan-induced diabetes in a dose-dependent manner, as demonstrated by a decrease in blood sugar, triglycerides, urea, creatinine, and cholesterol to 100?±?0.8, 57.66?±?0.8, 38?±?0.8, 1.11?±?0.08, 40?±?0.00?mg/dL, respectively, in rabbits administered with 300?mg/mL per kg BW AgNPs. The levels of oxidative stress markers (CAT, SOD, and GPx) in blood, that is, 3.6?±?0.08, 6.0?±?0.08, 918?±?2.0?IU/mL, respectively, were also increased in rabbits administered with 300?mg/mL per kg BW AgNPs. Our results conclude that synthesized AgNPs using aqueous extract of A. cepa peels have a protective effect against Alloxan-induced diabetes. äChemical Characterization, Antidiabetic and Antioxidant Potential of A(epmc).pdf DeepDyve Pubget Overpricing