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10.1136/bmjopen-2023-078370 http://scihub22266oqcxt.onion/10.1136/bmjopen-2023-078370 C11293378!11293378 !39089715     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=39089715 &cmd=llinks): Failed to open stream: HTTP request failed! 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Loss to follow-up and its predictors among children living with HIV on antiretroviral therapy, southern Oromia, Ethiopia: a 5-year retrospective cohort study |pdf=|usr=}}{{39089715 }} gab.com Text Loss to follow-up and its predictors among children living with HIV on antiretroviral therapy, southern Oromia, Ethiopia: a 5-year retrospective cohort study JO: BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=39089715 #FOAvip BACKGROUND: Loss to follow-up (LTFU) among paediatric patients living with HIV presents a significant challenge to the global scale-up of life-saving antiretroviral therapy (ART). OBJECTIVES: This study aims to estimate LTFU incidence and its determinants among children with HIV on ART in Shashemene town public health institutions, Oromia, Ethiopia. DESIGN: A retrospective cohort study from 1 January 2015 to 30 December 2020. SETTING: This study was conducted in Shashemene town, Oromia, Ethiopia. PARTICIPANTS: Medical records of 269 children receiving ART at health facilities in Shashemene town were included. METHODS: Data from patients' medical records were collected using a standardised checklist. EpiData V.3.1 was employed for data entry, while Statistical Package for the Social Sciences (SPSS) V.25 facilitated analysis. The Kaplan-Meier survival curve was used for estimation of survival time. To measure association, adjusted HRs (AHRs) with 95% CIs were calculated. Both bivariable and multivariable Cox proportional hazards regression models were employed to identify predictors of LTFU. RESULTS: Of the 269 children living with HIV included in the final analysis, 43 (16%) were lost to follow-up. The overall incidence rate of LTFU was 3.3 (95% CI 2.4 to 4.4) per 100 child-years of observation. Age less than 5 years (AHR 0.03, 95%?CI 0.00 to 0.36), non-orphan status of the child (AHR 0.13, 95% CI 0.05 to 0.34), < 30?min distance to health facility (AHR 0.24, 95%?CI 0.08 to 0.73), disclosed HIV status (AHR 0. 32, 95%?CI 0.13 to 0.80), history of opportunistic infection (AHR 3.54, 95% CI 1.15 to 10.87) and low CD4 count (AHR 5.17, 95% CI 2.08 to 12.85) were significant predictors of LTFU. CONCLUSION: The incidence rate of LTFU was lower compared with other studies in Ethiopia. This result indicated that age less than 5 years, non-orphans, low CD4, disclosed HIV status and distance from health facility were predictors of LTFU. Twit Text FOAVip Loss to follow-up and its predictors among children living with HIV on antiretroviral therapy, southern Oromia, Ethiopia: a 5-year retrospective cohort study ????BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=39089715 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=39089715 #FOAvip English Wikipedia <ref>{{Cite pmid|39089715 }}</ref> Loss to follow-up and its predictors among children living with HIV on antiretroviral therapy, southern Oromia, Ethiopia: a 5-year retrospective cohort study #MMPMID39089715 Bankere AW ; Daba SG ; Ami B ; Gedefa LK ; Lencha B BMJ Open 2024[Jul]; 14 (7 ): e078370 PMID39089715 show ga BACKGROUND: Loss to follow-up (LTFU) among paediatric patients living with HIV presents a significant challenge to the global scale-up of life-saving antiretroviral therapy (ART). OBJECTIVES: This study aims to estimate LTFU incidence and its determinants among children with HIV on ART in Shashemene town public health institutions, Oromia, Ethiopia. DESIGN: A retrospective cohort study from 1 January 2015 to 30 December 2020. SETTING: This study was conducted in Shashemene town, Oromia, Ethiopia. PARTICIPANTS: Medical records of 269 children receiving ART at health facilities in Shashemene town were included. METHODS: Data from patients' medical records were collected using a standardised checklist. EpiData V.3.1 was employed for data entry, while Statistical Package for the Social Sciences (SPSS) V.25 facilitated analysis. The Kaplan-Meier survival curve was used for estimation of survival time. To measure association, adjusted HRs (AHRs) with 95% CIs were calculated. Both bivariable and multivariable Cox proportional hazards regression models were employed to identify predictors of LTFU. RESULTS: Of the 269 children living with HIV included in the final analysis, 43 (16%) were lost to follow-up. The overall incidence rate of LTFU was 3.3 (95% CI 2.4 to 4.4) per 100 child-years of observation. Age less than 5 years (AHR 0.03, 95%?CI 0.00 to 0.36), non-orphan status of the child (AHR 0.13, 95% CI 0.05 to 0.34), < 30?min distance to health facility (AHR 0.24, 95%?CI 0.08 to 0.73), disclosed HIV status (AHR 0. 32, 95%?CI 0.13 to 0.80), history of opportunistic infection (AHR 3.54, 95% CI 1.15 to 10.87) and low CD4 count (AHR 5.17, 95% CI 2.08 to 12.85) were significant predictors of LTFU. CONCLUSION: The incidence rate of LTFU was lower compared with other studies in Ethiopia. This result indicated that age less than 5 years, non-orphans, low CD4, disclosed HIV status and distance from health facility were predictors of LTFU. |*HIV Infections/drug therapy/epidemiology [MESH] |*Lost to Follow-Up [MESH] |Adolescent [MESH] |Anti-HIV Agents/therapeutic use [MESH] |Anti-Retroviral Agents/therapeutic use [MESH] |Child [MESH] |Child, Preschool [MESH] |Ethiopia/epidemiology [MESH] |Female [MESH] |Humans [MESH] |Incidence [MESH] |Infant [MESH] |Kaplan-Meier Estimate [MESH] |Male [MESH] |Proportional Hazards Models [MESH] |Retrospective Studies [MESH]Loss to follow-up and its predictors among children living with HIV on(epmc).pdf DeepDyve Pubget Overpricing