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2024 ; 16
(7
): 2145-2156
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gab.com Text
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English Wikipedia
Correlation between abdominal computed tomography signs and postoperative
prognosis for patients with colorectal cancer
#MMPMID39087101
Yang SM
; Liu JM
; Wen RP
; Qian YD
; He JB
; Sun JS
World J Gastrointest Surg
2024[Jul]; 16
(7
): 2145-2156
PMID39087101
show ga
BACKGROUND: Patients with different stages of colorectal cancer (CRC) exhibit
different abdominal computed tomography (CT) signs. Therefore, the influence of
CT signs on CRC prognosis must be determined. AIM: To observe abdominal CT signs
in patients with CRC and analyze the correlation between the CT signs and
postoperative prognosis. METHODS: The clinical history and CT imaging results of
88 patients with CRC who underwent radical surgery at Xingtan Hospital Affiliated
to Shunde Hospital of Southern Medical University were retrospectively analyzed.
Univariate and multivariate Cox regression analyses were used to explore the
independent risk factors for postoperative death in patients with CRC. The
three-year survival rate was analyzed using the Kaplan-Meier curve, and the
correlation between postoperative survival time and abdominal CT signs in
patients with CRC was analyzed using Spearman correlation analysis. RESULTS: For
patients with CRC, the three-year survival rate was 73.86%. The death group
exhibited more severe characteristics than the survival group. A multivariate Cox
regression model analysis showed that body mass index (BMI), degree of
periintestinal infiltration, tumor size, and lymph node CT value were independent
factors influencing postoperative death (P < 0.05 for all). Patients with
characteristics typical to the death group had a low three-year survival rate
(log-rank ? (2) = 66.487, 11.346, 12.500, and 27.672, respectively, P < 0.05 for
all). The survival time of CRC patients was negatively correlated with BMI,
degree of periintestinal infiltration, tumor size, lymph node CT value, mean
tumor long-axis diameter, and mean tumor short-axis diameter (r = -0.559, 0.679,
-0.430, -0.585, -0.425, and -0.385, respectively, P < 0.05 for all). BMI was
positively correlated with the degree of periintestinal invasion, lymph node CT
value, and mean tumor short-axis diameter (r = 0.303, 0.431, and 0.437,
respectively, P < 0.05 for all). CONCLUSION: The degree of periintestinal
infiltration, tumor size, and lymph node CT value are crucial for evaluating the
prognosis of patients with CRC.