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http://scihub22266oqcxt.onion/ C110048!110048!9696879     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Virol 1998 ; 72 (9): 7697-702 Nephropedia Template TP {{tp|p=9696879|t=1998. The Nucleolus Is the Site of Borna Disease Virus RNA Transcription and Replication |pdf=|usr=}}{{9696879}} gab.com Text The Nucleolus Is the Site of Borna Disease Virus RNA Transcription and Replication JO: J Virol http://www.kidney.de/pget.php?&tw=1&pmid=9696879 #FOAvip Borna disease virus (BDV) is a neurotropic nonsegmented negative-strand RNA virus with limited homology to rhabdoviruses and paramyxoviruses. A distinguishing feature of BDV is that it replicates in the nucleus of infected cells. Strand-specific probes used for in situ hybridization of infected rat brain showed that there was differential localization of positive- and negative-strand RNAs within the nucleus of neurons. Within nuclei, sense-strand RNAs were preferentially localized within nucleolar regions while genomic-sense RNAs were found in both nucleolar and nonnucleolar regions. These results suggested a role for the nucleolus in BDV replication. Nucleoli isolated from persistently infected neuroblastoma cells contained both genomic and antigenomic BDV RNA species as well as an enrichment of the 39/38-kDa and gp18 BDV proteins. Since the nucleolus is the site of rRNA transcription, we examined BDV transcription in the presence of inhibitors of RNA polymerase I. Inhibition of RNA polymerase I did not affect levels of BDV transcription. Twit Text FOAVip The Nucleolus Is the Site of Borna Disease Virus RNA Transcription and Replication ????J Virol http://www.kidney.de/pget.php?&tw=1&pmid=9696879 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=9696879 #FOAvip English Wikipedia <ref>{{Cite pmid|9696879}}</ref> The Nucleolus Is the Site of Borna Disease Virus RNA Transcription and Replication #MMPMID9696879 Pyper JM; Clements JE; Zink MC J Virol 1998[Sep]; 72 (9): 7697-702 PMID9696879show ga Borna disease virus (BDV) is a neurotropic nonsegmented negative-strand RNA virus with limited homology to rhabdoviruses and paramyxoviruses. A distinguishing feature of BDV is that it replicates in the nucleus of infected cells. Strand-specific probes used for in situ hybridization of infected rat brain showed that there was differential localization of positive- and negative-strand RNAs within the nucleus of neurons. Within nuclei, sense-strand RNAs were preferentially localized within nucleolar regions while genomic-sense RNAs were found in both nucleolar and nonnucleolar regions. These results suggested a role for the nucleolus in BDV replication. Nucleoli isolated from persistently infected neuroblastoma cells contained both genomic and antigenomic BDV RNA species as well as an enrichment of the 39/38-kDa and gp18 BDV proteins. Since the nucleolus is the site of rRNA transcription, we examined BDV transcription in the presence of inhibitors of RNA polymerase I. Inhibition of RNA polymerase I did not affect levels of BDV transcription. äThe Nucleolus Is the Site of Borna Disease Virus RNA Transcription and(epmc).pdf DeepDyve Pubget Overpricing