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10.1007/BF01067012

http://scihub22266oqcxt.onion/10.1007/BF01067012
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988552!ä!988552

suck abstract from ncbi


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pmid988552      Pflugers+Arch 1976 ; 365 (2-3): 151-7
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  • The influence of CSF calcium and magnesium on the ventilatory response to carbon dioxide during hyperoxia #MMPMID988552
  • Berkenbosch A; Quanjer PH; De Goede J; Tammeling GJ
  • Pflugers Arch 1976[Sep]; 365 (2-3): 151-7 PMID988552show ga
  • Respiratory responses to inhaled carbon dioxide were measured in anaesthetized cats during perfusion of the ventriculocisternal system with artificial cerebrospinal fluid. A study was performed to evaluate the effect of changes in the magnesium and/or calcium concentration of the CSF on the CO2 response curve which was described as VE = S (PCSF, CO2 -- B). A decrease of S was observed when the magnesium concentration of the perfusion fluid was increased; the B-value remaining the same. The reverse was true down to magnesium concentrations of 0.6 mmol-1-1. Below this concentration S remained the same or decreased; the B-value was lowered. When both the calcium and magnesium concentrations of the CSF were changed, the relation between S and these concentrations could be described as to be proportional to CCAa-CMgb. The effect of changes in the calcium concentration was much more pronounced than comparable changes of the magnesium concentration as reflected by the magnitude of the exponents a and b which were found to be -2.80 (S.D. 0.11) and -0.60 (S.D. 0.03) respectively.
  • |*Respiration[MESH]
  • |Animals[MESH]
  • |Calcium/*cerebrospinal fluid[MESH]
  • |Carbon Dioxide/cerebrospinal fluid[MESH]
  • |Cats[MESH]
  • |Magnesium/*cerebrospinal fluid[MESH]


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