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10.1006/cimm.1998.1295 http://scihub22266oqcxt.onion/10.1006/cimm.1998.1295 9637759!ä!9637759 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Immunol 1998 ; 186 (1): 1-7 Nephropedia Template TP {{tp|p=9637759|t=1998. Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated influenza A virus |pdf=|usr=}}{{9637759}} gab.com Text Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated influenza A virus JO: Cell Immunol http://www.kidney.de/pget.php?&tw=1&pmid=9637759 #FOAvip After influenza A virus infection of human monocytes, we found a rapid and marked release of the mononuclear cell attracting chemokines MCP-1, MIP-1 alpha, and IP-10, with corresponding gene expression patterns as determined by Northern blot analysis. In striking contrast, the expression and release of the neutrophil chemoattractant IL-8 was not inducible. To determine the underlying mechanisms responsible for the induction of this differential chemokine pattern, we stimulated monocytes with UV- and heat-inactivated (56 degrees C and 100 degrees C) influenza A virus. In comparison with fully infectious influenza A, 56 degrees C-inactivated virus induced a strong production of MCP-1, MIP-1 alpha, and IP-10, while the release of MIP-1 alpha and IP-10 was substantially lower after exposure to UV-inactivated virus. No chemokine expression was found after stimulation with 100 degrees C-inactivated influenza A virus. Our data indicate that, contingent upon the chemokine examined, the maximal induction depends on the unrestricted infectivity of the virus, the unaltered hemagglutinin molecule, or the intact viral RNA. This diversified chemokine production may enable the infected host to mount an efficient antiviral response against infective and noninfective virus particles. Twit Text FOAVip Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated influenza A virus ????Cell Immunol http://www.kidney.de/pget.php?&tw=1&pmid=9637759 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=9637759 #FOAvip English Wikipedia <ref>{{Cite pmid|9637759}}</ref> Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated influenza A virus #MMPMID9637759 Bussfeld D; Kaufmann A; Meyer RG; Gemsa D; Sprenger H Cell Immunol 1998[May]; 186 (1): 1-7 PMID9637759show ga After influenza A virus infection of human monocytes, we found a rapid and marked release of the mononuclear cell attracting chemokines MCP-1, MIP-1 alpha, and IP-10, with corresponding gene expression patterns as determined by Northern blot analysis. In striking contrast, the expression and release of the neutrophil chemoattractant IL-8 was not inducible. To determine the underlying mechanisms responsible for the induction of this differential chemokine pattern, we stimulated monocytes with UV- and heat-inactivated (56 degrees C and 100 degrees C) influenza A virus. In comparison with fully infectious influenza A, 56 degrees C-inactivated virus induced a strong production of MCP-1, MIP-1 alpha, and IP-10, while the release of MIP-1 alpha and IP-10 was substantially lower after exposure to UV-inactivated virus. No chemokine expression was found after stimulation with 100 degrees C-inactivated influenza A virus. Our data indicate that, contingent upon the chemokine examined, the maximal induction depends on the unrestricted infectivity of the virus, the unaltered hemagglutinin molecule, or the intact viral RNA. This diversified chemokine production may enable the infected host to mount an efficient antiviral response against infective and noninfective virus particles. |Animals[MESH] |Cell Line[MESH] |Chemokine CCL2/*biosynthesis/genetics[MESH] |Chemokine CCL4[MESH] |Chemokine CXCL10[MESH] |Chemokines, CXC/*biosynthesis/genetics[MESH] |Chickens[MESH] |Dogs[MESH] |Gene Expression[MESH] |Hemagglutinin Glycoproteins, Influenza Virus/metabolism[MESH] |Humans[MESH] |Influenza A virus/*physiology[MESH] |Interferon-alpha/analysis[MESH] |Interferon-beta/analysis[MESH] |Interleukin-8/genetics[MESH] |Lymphotoxin-alpha/analysis[MESH] |Macrophage Inflammatory Proteins/*biosynthesis/genetics[MESH] |Monocytes/*immunology/virology[MESH]Differential mononuclear leukocyte attracting chemokine production aft(epmc).pdf DeepDyve Pubget Overpricing