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10.1007/s004670050296

http://scihub22266oqcxt.onion/10.1007/s004670050296
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9203192!ä!9203192

suck abstract from ncbi


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pmid9203192      Pediatr+Nephrol 1997 ; 11 (3): 355-7
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  • Chronic anemia as a complication of parvovirus B19 infection in a pediatric kidney transplant patient #MMPMID9203192
  • Mathias RS
  • Pediatr Nephrol 1997[Jun]; 11 (3): 355-7 PMID9203192show ga
  • This is a report of unexplained anemia that persisted for 4 months in an adolescent renal transplant patient receiving immunosuppression that included prednisone, tacrolimus, and mycophenolate mofetil. This patient required monthly blood transfusions for fatigue, palpitations, and hematocrit levels between 15% and 17%. In addition, his posttransplant course was notable for the development of insulin-dependent diabetes mellitus. While receiving low-dose prednisone, he was switched from tacrolimus to cyclosporin and tapered off insulin injections over the next 2 months. At 4.5 months post-transplantation, further diagnostic evaluation was suggestive of parvovirus B19 infection as the cause for our patient's chronic anemia. After testing negative for serum-specific parvovirus B19 IgM and IgG antibodies, parvovirus B19 infection was detected in blood by the polymerase chain reaction. Treatment with intravenous immunoglobulin (1 g/kg per day x 2 days) resulted in normalization of both his reticulocyte count and hematocrit within 6 weeks. At 4 months after receiving the immunoglobulin infusion, he has maintained a normal hematocrit level and stable renal function without requiring further blood transfusions.
  • |*Parvovirus B19, Human[MESH]
  • |Adolescent[MESH]
  • |Anemia/blood/*etiology[MESH]
  • |Chronic Disease[MESH]
  • |Hematocrit[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents/adverse effects/therapeutic use[MESH]
  • |Kidney Function Tests[MESH]
  • |Kidney Transplantation/*physiology[MESH]
  • |Male[MESH]
  • |Parvoviridae Infections/*blood[MESH]


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