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10.1016/s0925-4773(97)00667-9 http://scihub22266oqcxt.onion/10.1016/s0925-4773(97)00667-9 9152004!ä!9152004 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\9152004.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mech+Dev 1997 ; 62 (2): 105-20 Nephropedia Template TP {{tp|p=9152004|t=1997. The molecular basis of embryonic kidney development |pdf=|usr=}}{{9152004}} gab.com Text The molecular basis of embryonic kidney development JO: Mech Dev http://www.kidney.de/pget.php?&tw=1&pmid=9152004 #FOAvip The development of the mature mammalian kidney begins with the invasion of metanephric mesenchyme by ureteric bud. Mesenchymal cells near the bud become induced and convert to an epithelium which goes on to generate the functional filtering unit of the kidney, the nephron. The collecting duct system is elaborated by the branching ureter, the growth of which is dependent upon signals from the metanephric mesenchyme. The process of reciprocal induction between ureter and mesenchyme is repeated many times over during development and is the key step in generating the overall architecture of the kidney. Genetic studies in mice have allowed researchers to begin to unravel the molecular signals that govern these early events. These experiments have revealed that a number of essential gene products are required for distinct steps in kidney organogenesis. Here we review and summarize the developmental role played by some of these molecules, especially certain transcription factors and growth factors and their receptors. Although the factors involved are far from completely known a rough framework of a molecular cascade which governs embryonic kidney development is beginning to emerge. Twit Text FOAVip The molecular basis of embryonic kidney development ????Mech Dev http://www.kidney.de/pget.php?&tw=1&pmid=9152004 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=9152004 #FOAvip English Wikipedia <ref>{{Cite pmid|9152004}}</ref> The molecular basis of embryonic kidney development #MMPMID9152004 Lechner MS; Dressler GR Mech Dev 1997[Mar]; 62 (2): 105-20 PMID9152004show ga The development of the mature mammalian kidney begins with the invasion of metanephric mesenchyme by ureteric bud. Mesenchymal cells near the bud become induced and convert to an epithelium which goes on to generate the functional filtering unit of the kidney, the nephron. The collecting duct system is elaborated by the branching ureter, the growth of which is dependent upon signals from the metanephric mesenchyme. The process of reciprocal induction between ureter and mesenchyme is repeated many times over during development and is the key step in generating the overall architecture of the kidney. Genetic studies in mice have allowed researchers to begin to unravel the molecular signals that govern these early events. These experiments have revealed that a number of essential gene products are required for distinct steps in kidney organogenesis. Here we review and summarize the developmental role played by some of these molecules, especially certain transcription factors and growth factors and their receptors. Although the factors involved are far from completely known a rough framework of a molecular cascade which governs embryonic kidney development is beginning to emerge. |*Drosophila Proteins[MESH] |*Nerve Growth Factors[MESH] |*Transforming Growth Factor beta[MESH] |Animals[MESH] |Apoptosis/physiology[MESH] |Bone Morphogenetic Protein 7[MESH] |Bone Morphogenetic Proteins/physiology[MESH] |Cell Division/physiology[MESH] |Embryonic and Fetal Development[MESH] |Glial Cell Line-Derived Neurotrophic Factor[MESH] |Glial Cell Line-Derived Neurotrophic Factor Receptors[MESH] |Glycoproteins/physiology[MESH] |Growth Substances/*physiology[MESH] |Kidney/*embryology[MESH] |Mice[MESH] |Nerve Tissue Proteins/physiology[MESH] |Proto-Oncogene Proteins c-ret[MESH] |Proto-Oncogene Proteins/physiology[MESH] |Receptor Protein-Tyrosine Kinases/physiology[MESH] |Transcription Factors/physiology[MESH] |Wnt Proteins[MESH]The molecular basis of embryonic kidney development (epmc).pdf DeepDyve Pubget Overpricing