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Technetium-99m-MAG3 scintigraphy in acute renal failure after transplantation: a marker of viability and prognosis |pdf=|usr=}}{{9074542}} gab.com Text Technetium-99m-MAG3 scintigraphy in acute renal failure after transplantation: a marker of viability and prognosis JO: J Nucl Med http://www.kidney.de/pget.php?&tw=1&pmid=9074542 #FOAvip This study assessed 99mTc-mercaptoacetyltriglycine (MAG3) for determination of renal transplant prognosis for recovery in patients with early postoperative dysfunction. The postulate tested was that good tracer extraction may imply high likelihood of recovery, while poor extraction may confer a poor prognosis. METHODS: A 2-min image acquired 1 min after MAG3 administration, named a cortical uptake phase (CUP) image, was visually analyzed according to standardized semiquantitative guidelines. Interpretation was expressed in tubular injury severity scores (TISS) that ranged from 1 (a normally functioning renal transplant) to 6 (a photopenic defect in place of renal transplant). RESULTS: The study analyzed 64 patients (35 men, 29 women, age 45.9 +/- 14 yr). All five patients with TISS of 6 or 5 lost the transplant. Only 1 of 10 patients with TISS of 4 lost the transplant. All patients with TISS of less than 4 recovered renal transplant function. CONCLUSION: This study suggests that MAG3 scan (the CUP image specifically) is an accurate prognosticator in patients with early postoperative renal transplant dysfunction. Reproduction of these results in a larger population and other institutions is necessary before clinical implementation of this methodology. Twit Text FOAVip Technetium-99m-MAG3 scintigraphy in acute renal failure after transplantation: a marker of viability and prognosis ????J Nucl Med http://www.kidney.de/pget.php?&tw=1&pmid=9074542 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=9074542 #FOAvip English Wikipedia <ref>{{Cite pmid|9074542}}</ref> Technetium-99m-MAG3 scintigraphy in acute renal failure after transplantation: a marker of viability and prognosis #MMPMID9074542 Tulchinsky M; Dietrich TJ; Eggli DF; Yang HC J Nucl Med 1997[Mar]; 38 (3): 475-8 PMID9074542show ga This study assessed 99mTc-mercaptoacetyltriglycine (MAG3) for determination of renal transplant prognosis for recovery in patients with early postoperative dysfunction. The postulate tested was that good tracer extraction may imply high likelihood of recovery, while poor extraction may confer a poor prognosis. METHODS: A 2-min image acquired 1 min after MAG3 administration, named a cortical uptake phase (CUP) image, was visually analyzed according to standardized semiquantitative guidelines. Interpretation was expressed in tubular injury severity scores (TISS) that ranged from 1 (a normally functioning renal transplant) to 6 (a photopenic defect in place of renal transplant). RESULTS: The study analyzed 64 patients (35 men, 29 women, age 45.9 +/- 14 yr). All five patients with TISS of 6 or 5 lost the transplant. Only 1 of 10 patients with TISS of 4 lost the transplant. All patients with TISS of less than 4 recovered renal transplant function. CONCLUSION: This study suggests that MAG3 scan (the CUP image specifically) is an accurate prognosticator in patients with early postoperative renal transplant dysfunction. Reproduction of these results in a larger population and other institutions is necessary before clinical implementation of this methodology. |*Kidney Transplantation[MESH] |*Radiopharmaceuticals/pharmacokinetics[MESH] |*Technetium Tc 99m Mertiatide/pharmacokinetics[MESH] |Acute Kidney Injury/*surgery[MESH] |Adult[MESH] |Chi-Square Distribution[MESH] |Female[MESH] |Follow-Up Studies[MESH] |Humans[MESH] |Kidney/*diagnostic imaging/metabolism[MESH] |Male[MESH] |Middle Aged[MESH] |Prognosis[MESH] |Radionuclide Imaging[MESH]Technetium-99m-MAG3 scintigraphy in acute renal failure after transpla(epmc).pdf DeepDyve Pubget Overpricing