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10.1046/j.1365-2141.1997.d01-2099.x

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9074434!ä!9074434

suck abstract from ncbi


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pmid9074434      Br+J+Haematol 1997 ; 96 (4): 868-71
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  • Parvovirus B19-associated haemophagocytic syndrome with lymphadenopathy resembling histiocytic necrotizing lymphadenitis (Kikuchi s disease) #MMPMID9074434
  • Yufu Y; Matsumoto M; Miyamura T; Nishimura J; Nawata H; Ohshima K
  • Br J Haematol 1997[Mar]; 96 (4): 868-71 PMID9074434show ga
  • A 15-year-old girl developed a haemophagocytic syndrome caused by human parvovirus B19 (PVB19). The cervical lymph node histology, resembling that of histiocytic necrotizing lymphadenitis (HNL, Kikuchi's disease), included several transformed lymphocytes, numerous histocytes, and massive necrosis. We detected PVB19-positive cells in the lymph node by immunohistochemistry. Possible autoimmune mechanisms in HNL-like diseases triggered by PVB19 are discussed.
  • |Adolescent[MESH]
  • |Female[MESH]
  • |Histiocytosis, Non-Langerhans-Cell/drug therapy/*virology[MESH]
  • |Humans[MESH]
  • |Immunohistochemistry[MESH]
  • |Lymphadenitis/drug therapy/*virology[MESH]
  • |Necrosis[MESH]
  • |Parvoviridae Infections/*complications/drug therapy[MESH]
  • |Parvovirus B19, Human[MESH]
  • |Prednisolone/therapeutic use[MESH]


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