Parvovirus B19 infection in Behcet s disease #MMPMID8697661
Kiraz S; Ertenli I; Benekli M; Calguneri M
Clin Exp Rheumatol 1996[Jan]; 14 (1): 71-3 PMID8697661show ga
OBJECTIVE: To investigate whether parvovirus B19 infection is associated with Behcet's disease (BD). METHODS: Serum samples from 41 patients with BD and from 40 age- and sex-matched controls were studied. An ELISA assay was used to detect antibodies against parvovirus B19. RESULTS: Six patients with BD (15.7%) had anti-B19 IgM antibodies in their serum samples indicating a recent infection, while no positivity for IgM antibodies was detected in the control group (p = 0.03). CONCLUSION: Although there have been several reports of B19 infection associated with vasculitis, our findings do not strongly support the involvement of B19 in the pathogenesis of BD. The serological evidence of acute infection in 6 BD patients may be purely coincidental. There was also no positive correlation with the articular and vascular manifestations of BD.
Clin+Exp+Rheumatol 1996 ; 14 (1): 71-3
