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10.1097/00000441-199304000-00007

http://scihub22266oqcxt.onion/10.1097/00000441-199304000-00007
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8475949!ä!8475949

suck abstract from ncbi


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pmid8475949      Am+J+Med+Sci 1993 ; 305 (4): 236-40
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  • Case report: pentamidine and polymorphic ventricular tachycardia revisited #MMPMID8475949
  • Mani S; Kocheril AG; Andriole VT
  • Am J Med Sci 1993[Apr]; 305 (4): 236-40 PMID8475949show ga
  • Pentamidine isethionate has been associated with ventricular tachyarrhythmias, including torsade de pointes. This article reports two cases of this complication and reviews all reported cases to date. Pentamidine-induced torsade de pointes may be related to serum magnesium levels and hypomagnesemia may synergistically induce torsade. Torsade de pointes occurred after an average of 10 days of treatment with pentamidine. In these patients, no other acute side effects of pentamidine were observed. Torsade de pointes can be treated when recognized early, possibly without discontinuation of pentamidine. When QTc interval prolongation is observed, early magnesium supplementation is advocated.
  • |Adult[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pentamidine/*adverse effects[MESH]
  • |Pneumonia, Pneumocystis/drug therapy[MESH]


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