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10.1016/0165-0327(93)90098-5 http://scihub22266oqcxt.onion/10.1016/0165-0327(93)90098-5 8432962!ä!8432962 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Affect+Disord 1993 ; 27 (1): 61-8 Nephropedia Template TP {{tp|p=8432962|t=1993. Detection of Borna disease virus-reactive antibodies from patients with affective disorders by western immunoblot technique |pdf=|usr=}}{{8432962}} gab.com Text Detection of Borna disease virus-reactive antibodies from patients with affective disorders by western immunoblot technique JO: J Affect Disord http://www.kidney.de/pget.php?&tw=1&pmid=8432962 #FOAvip Borna disease (BD) virus is a partially characterized neurotropic agent with a predilection for neurons and astrocytes in the limbic system and cerebrum of infected hosts. Although it usually causes a fatal encephalitis, some laboratory animals which have been experimentally inoculated can develop a persistent non-fatal infection characterized by a neuro-behavioral syndrome akin to human manic-depression. Using immunofluorescent techniques, we previously observed BD virus-specific antibodies in the sera of 4.5% of affectively ill patients, with the highest titers present in bipolar patients. More recently, we have developed a sensitive Western blot assay for the detection of anti-BD virus antibodies to a 38/40 kDa and 24 kDa protein in human serum. In the present study, we screened 138 affectively ill patients and 117 healthy controls and observed a significantly great proportion of patients with antibodies to the 38/40 kDa protein (P < 0.0001), the 24 kDa protein (P < 0.05) and both the 38/40 kDa and 24 kDa proteins (P < 0.025). These data extend prior reports on the presence of BD virus-specific antibodies in psychiatric patients, and suggest that a BD virus-like agent may be associated with affective illness in humans. Twit Text FOAVip Detection of Borna disease virus-reactive antibodies from patients with affective disorders by western immunoblot technique ????J Affect Disord http://www.kidney.de/pget.php?&tw=1&pmid=8432962 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=8432962 #FOAvip English Wikipedia <ref>{{Cite pmid|8432962}}</ref> Detection of Borna disease virus-reactive antibodies from patients with affective disorders by western immunoblot technique #MMPMID8432962 Fu ZF; Amsterdam JD; Kao M; Shankar V; Koprowski H; Dietzschold B J Affect Disord 1993[Jan]; 27 (1): 61-8 PMID8432962show ga Borna disease (BD) virus is a partially characterized neurotropic agent with a predilection for neurons and astrocytes in the limbic system and cerebrum of infected hosts. Although it usually causes a fatal encephalitis, some laboratory animals which have been experimentally inoculated can develop a persistent non-fatal infection characterized by a neuro-behavioral syndrome akin to human manic-depression. Using immunofluorescent techniques, we previously observed BD virus-specific antibodies in the sera of 4.5% of affectively ill patients, with the highest titers present in bipolar patients. More recently, we have developed a sensitive Western blot assay for the detection of anti-BD virus antibodies to a 38/40 kDa and 24 kDa protein in human serum. In the present study, we screened 138 affectively ill patients and 117 healthy controls and observed a significantly great proportion of patients with antibodies to the 38/40 kDa protein (P < 0.0001), the 24 kDa protein (P < 0.05) and both the 38/40 kDa and 24 kDa proteins (P < 0.025). These data extend prior reports on the presence of BD virus-specific antibodies in psychiatric patients, and suggest that a BD virus-like agent may be associated with affective illness in humans. |Adult[MESH] |Antibodies, Viral/*analysis[MESH] |Bipolar Disorder/*diagnosis/immunology/psychology[MESH] |Blotting, Western[MESH] |Borna Disease/*diagnosis/immunology/psychology[MESH] |Borna disease virus/*immunology[MESH] |Chronic Disease[MESH] |Depressive Disorder/*diagnosis/immunology/psychology[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Middle Aged[MESH]Detection of Borna disease virus-reactive antibodies from patients wit(epmc).pdf DeepDyve Pubget Overpricing