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10.1016/s0025-6196(12)62252-6 http://scihub22266oqcxt.onion/10.1016/s0025-6196(12)62252-6 8189766!?!8189766 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=8189766&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Mayo+Clin+Proc 1994 ; 69 (6): 589-93 Nephropedia Template TP {{tp|p=8189766|t=1994. Torsades de pointes ventricular tachycardia associated with overdose of astemizole |pdf=|usr=}}{{8189766}} gab.com Text Torsades de pointes ventricular tachycardia associated with overdose of astemizole JO: Mayo Clin Proc http://www.kidney.de/pget.php?&tw=1&pmid=8189766 #FOAvip An overdose of astemizole predisposes the myocardium to ventricular dysrhythmias, including torsades de pointes. Herein we describe a case of astemizole-induced torsades de pointes ventricular tachycardia and also review previous case reports in the literature. All the patients were young, and dysrhythmias developed only in those with corrected QT intervals greater than 500 ms. Although several mechanisms have been postulated, no clear explanation has been provided for why astemizole promotes myocardial dysrhythmias. Treatment of astemizole-induced torsades de pointes includes discontinuing use of astemizole, intravenous administration of magnesium sulfate and isoproterenol, temporary cardiac pacing, and, when necessary, direct current cardioversion. A cardiac cause of syncope or convulsions must not be overlooked, especially in patients taking H1 antagonists because they often have these symptoms before hospitalization or detection of torsades de pointes (or both). Twit Text FOAVip Torsades de pointes ventricular tachycardia associated with overdose of astemizole ????Mayo Clin Proc http://www.kidney.de/pget.php?&tw=1&pmid=8189766 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=8189766 #FOAvip English Wikipedia <ref>{{Cite pmid|8189766}}</ref> Torsades de pointes ventricular tachycardia associated with overdose of astemizole #MMPMID8189766 Rao KA; Adlakha A; Verma-Ansil B; Meloy TD; Stanton MS Mayo Clin Proc 1994[Jun]; 69 (6): 589-93 PMID8189766show ga An overdose of astemizole predisposes the myocardium to ventricular dysrhythmias, including torsades de pointes. Herein we describe a case of astemizole-induced torsades de pointes ventricular tachycardia and also review previous case reports in the literature. All the patients were young, and dysrhythmias developed only in those with corrected QT intervals greater than 500 ms. Although several mechanisms have been postulated, no clear explanation has been provided for why astemizole promotes myocardial dysrhythmias. Treatment of astemizole-induced torsades de pointes includes discontinuing use of astemizole, intravenous administration of magnesium sulfate and isoproterenol, temporary cardiac pacing, and, when necessary, direct current cardioversion. A cardiac cause of syncope or convulsions must not be overlooked, especially in patients taking H1 antagonists because they often have these symptoms before hospitalization or detection of torsades de pointes (or both). |Adult[MESH] |Astemizole/*adverse effects[MESH] |Drug Overdose/therapy[MESH] |Electrocardiography[MESH] |Female[MESH] |Humans[MESH] |Rhinitis, Vasomotor/drug therapy[MESH]Torsades de pointes ventricular tachycardia associated with overdose o(epmc).pdf DeepDyve Pubget Overpricing