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10.1042/cs0870021 http://scihub22266oqcxt.onion/10.1042/cs0870021 8062515!ä!8062515 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Sci+(Lond) 1994 ; 87 (1): 21-9 Nephropedia Template TP {{tp|p=8062515|t=1994. Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications |pdf=|usr=}}{{8062515}} gab.com Text Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications JO: Clin Sci (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=8062515 #FOAvip 1. The metabolism of methylglyoxal by the glyoxalase system may be linked to the development of diabetic complications. The glyoxalase system was characterized in blood samples from patients with insulin-dependent diabetes mellitus (n = 43), patients with non-insulin-dependent diabetes mellitus (n = 107) and 21 normal healthy control subjects. 2. The concentrations of glyoxalase metabolites, methylglyoxal, S-D-lactoylglutathione and D-lactate, were increased in diabetic patients, relative to normal control subjects: methylglyoxal [median, range (n) pmol/g], insulin-dependent patients, 470.7, 85.6-1044.3 (42), P < 0.001, non-insulin-dependent patients, 286.8, 54.7-2370 (105), P < 0.001, control subjects, 79.8, 25.3-892.9 (21); S-D-lactoylglutathione [mean +/- SD (n)pmol/10(6) erythrocytes], combined diabetic patients, 3.37 +/- 0.85 (24), control subjects 4.76 +/- 1.95 (8) P < 0.05; D-lactate [mean +/- SD or median, range (n)nmol/g], insulin dependent patients, median 18.3, 5.7-57.4 (42), P < 0.001, non-insulin-dependent patients, 20.0 +/- 8.9, 2.6-48.4 (105), P < 0.001, control subjects 9.7 +/- 4.3, 1.8-19.7 (21). The reduced glutathione concentrations in blood samples from the insulin-dependent and non-insulin-dependent diabetic patient groups were not different from the control group values (P > 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) Twit Text FOAVip Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications ????Clin Sci (Lond) http://www.kidney.de/pget.php?&tw=1&pmid=8062515 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=8062515 #FOAvip English Wikipedia <ref>{{Cite pmid|8062515}}</ref> Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications #MMPMID8062515 McLellan AC; Thornalley PJ; Benn J; Sonksen PH Clin Sci (Lond) 1994[Jul]; 87 (1): 21-9 PMID8062515show ga 1. The metabolism of methylglyoxal by the glyoxalase system may be linked to the development of diabetic complications. The glyoxalase system was characterized in blood samples from patients with insulin-dependent diabetes mellitus (n = 43), patients with non-insulin-dependent diabetes mellitus (n = 107) and 21 normal healthy control subjects. 2. The concentrations of glyoxalase metabolites, methylglyoxal, S-D-lactoylglutathione and D-lactate, were increased in diabetic patients, relative to normal control subjects: methylglyoxal [median, range (n) pmol/g], insulin-dependent patients, 470.7, 85.6-1044.3 (42), P < 0.001, non-insulin-dependent patients, 286.8, 54.7-2370 (105), P < 0.001, control subjects, 79.8, 25.3-892.9 (21); S-D-lactoylglutathione [mean +/- SD (n)pmol/10(6) erythrocytes], combined diabetic patients, 3.37 +/- 0.85 (24), control subjects 4.76 +/- 1.95 (8) P < 0.05; D-lactate [mean +/- SD or median, range (n)nmol/g], insulin dependent patients, median 18.3, 5.7-57.4 (42), P < 0.001, non-insulin-dependent patients, 20.0 +/- 8.9, 2.6-48.4 (105), P < 0.001, control subjects 9.7 +/- 4.3, 1.8-19.7 (21). The reduced glutathione concentrations in blood samples from the insulin-dependent and non-insulin-dependent diabetic patient groups were not different from the control group values (P > 0.05).(ABSTRACT TRUNCATED AT 250 WORDS) |Adult[MESH] |Diabetes Mellitus, Type 1/blood/enzymology[MESH] |Diabetes Mellitus, Type 2/blood/enzymology[MESH] |Diabetes Mellitus/*enzymology[MESH] |Diabetic Nephropathies/metabolism[MESH] |Diabetic Neuropathies/metabolism[MESH] |Diabetic Retinopathy/metabolism[MESH] |Erythrocytes/enzymology[MESH] |Female[MESH] |Glutathione/analogs & derivatives/blood[MESH] |Glycated Hemoglobin/*metabolism[MESH] |Growth Inhibitors/blood[MESH] |Humans[MESH] |Lactates/blood[MESH] |Lactic Acid[MESH] |Lactoylglutathione Lyase/*metabolism[MESH] |Male[MESH] |Middle Aged[MESH] |Pyruvaldehyde/blood[MESH]Glyoxalase system in clinical diabetes mellitus and correlation with d(epmc).pdf DeepDyve Pubget Overpricing