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10.3109/08037059409102262 http://scihub22266oqcxt.onion/10.3109/08037059409102262 7994447!ä!7994447 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Blood+Press 1994 ; 3 (4): 231-5 Nephropedia Template TP {{tp|p=7994447|t=1994. Relation between low dose of hydrochlorothiazide, antihypertensive effect and adverse effects |pdf=|usr=}}{{7994447}} gab.com Text Relation between low dose of hydrochlorothiazide, antihypertensive effect and adverse effects JO: Blood Press http://www.kidney.de/pget.php?&tw=1&pmid=7994447 #FOAvip Thiazide diuretics are widely used in the drug treatment of hypertension but their dose-response curves for the antihypertensive and adverse metabolic effects differ. To characterize the lower end of the dose-response curve a double-blind, parallel group trial was performed as multicentre study in Scandinavia. One hundred and eleven patients with newly diagnosed or previously treated mild to moderate hypertension (untreated diastolic blood pressure of 95-115 mmHg after 4 weeks placebo) were randomly allocated to various doses of hydrochlorothiazide (3, 6, 12.5 or 25 mg) or placebo for 6 weeks. Blood pressure and biochemical variables (plasma renin activity, serum potassium, magnesium, urate, fasting glucose, total cholesterol, HDL-cholesterol, triglycerides and apolipoproteins A1 and B were measured. 12.5 mg hydrochlorothiazide had a borderline effect on blood pressure whilst 25 mg had a definite antihypertensive effect. Biochemical changes were seen in plasma renin activity, serum potassium and urate after the 12.5 and 25 mg dose. Three and 6 mg had no effect on blood pressure or metabolic parameters. Twit Text FOAVip Relation between low dose of hydrochlorothiazide, antihypertensive effect and adverse effects ????Blood Press http://www.kidney.de/pget.php?&tw=1&pmid=7994447 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=7994447 #FOAvip English Wikipedia <ref>{{Cite pmid|7994447}}</ref> Relation between low dose of hydrochlorothiazide, antihypertensive effect and adverse effects #MMPMID7994447 Jounela AJ; Lilja M; Lumme J; Morlin C; Hoyem A; Wessel-Aas T; Borrild NJ Blood Press 1994[Jul]; 3 (4): 231-5 PMID7994447show ga Thiazide diuretics are widely used in the drug treatment of hypertension but their dose-response curves for the antihypertensive and adverse metabolic effects differ. To characterize the lower end of the dose-response curve a double-blind, parallel group trial was performed as multicentre study in Scandinavia. One hundred and eleven patients with newly diagnosed or previously treated mild to moderate hypertension (untreated diastolic blood pressure of 95-115 mmHg after 4 weeks placebo) were randomly allocated to various doses of hydrochlorothiazide (3, 6, 12.5 or 25 mg) or placebo for 6 weeks. Blood pressure and biochemical variables (plasma renin activity, serum potassium, magnesium, urate, fasting glucose, total cholesterol, HDL-cholesterol, triglycerides and apolipoproteins A1 and B were measured. 12.5 mg hydrochlorothiazide had a borderline effect on blood pressure whilst 25 mg had a definite antihypertensive effect. Biochemical changes were seen in plasma renin activity, serum potassium and urate after the 12.5 and 25 mg dose. Three and 6 mg had no effect on blood pressure or metabolic parameters. |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Blood Pressure/drug effects[MESH] |Dose-Response Relationship, Drug[MESH] |Double-Blind Method[MESH] |Female[MESH] |Humans[MESH] |Hydrochlorothiazide/administration & dosage/adverse effects/*therapeutic use[MESH] |Hypertension/*drug therapy[MESH] |Male[MESH] |Middle Aged[MESH]Relation between low dose of hydrochlorothiazide, antihypertensive eff(epmc).pdf DeepDyve Pubget Overpricing