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Borna disease in naturally infected cattle #MMPMID7962728
Caplazi P; Waldvogel A; Stitz L; Braun U; Ehrensperger F
J Comp Pathol 1994[Jul]; 111 (1): 65-72 PMID7962728show ga
Based on the immunohistochemical demonstration of viral antigen and on the histological brain lesions, Borna disease was diagnosed in a cow and a bull which had suffered from a severe, subacute progressive disorder of the central nervous system. Virus-specific antigen was characteristically localized in neurons, predominantly in the perikaryon and dendrites. In a serum sample available from one of the animals a Borna disease virus antibody titre of 1 in 80 was demonstrated. This is the first report of the natural disease in cattle.