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10.1288/00005537-199410000-00009

http://scihub22266oqcxt.onion/10.1288/00005537-199410000-00009
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7934594!ä!7934594

suck abstract from ncbi


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pmid7934594      Laryngoscope 1994 ; 104 (10): 1235-9
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  • Immune-mediated inner ear disease and parvovirus B19 #MMPMID7934594
  • Cotter CS; Singleton GT; Corman LC
  • Laryngoscope 1994[Oct]; 104 (10): 1235-9 PMID7934594show ga
  • Human parvovirus B19 (HP-B19), the etiologic agent of the common childhood illness erythema infectiosum, has been implicated in systemic immune disorders. Patients presenting with sensorineural hearing loss and/or dizziness, not readily categorized, were evaluated for immune-mediated inner ear disease. Appropriate serologic studies including parvovirus B19 antibody titers were conducted. Thirty patients with suspected immune-mediated inner ear disease were treated with corticosteroid trial for 5 to 7 days, then reexamined with repeat audiogram and/or vestibular testing. Seventeen patients with clinical response were treated with long-term corticosteroids and cyclophosphamide. Six patients had positive HP-B19 immunoglobulin M (IgM) titers and 8 patients had positive parvovirus immunoglobulin G (IgG) titers. All 14 patients responded to therapy. Parvovirus B19, therefore, is a possible etiology of immune-mediated inner ear disease.
  • |Adrenal Cortex Hormones/therapeutic use[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Antibodies, Viral/analysis[MESH]
  • |Autoimmune Diseases/drug therapy/*immunology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Cyclophosphamide/therapeutic use[MESH]
  • |Erythema Infectiosum/*complications/immunology[MESH]
  • |Female[MESH]
  • |Hearing Loss, Sensorineural/drug therapy/etiology[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents/therapeutic use[MESH]
  • |Labyrinth Diseases/drug therapy/*immunology/*virology[MESH]
  • |Male[MESH]
  • |Methotrexate/therapeutic use[MESH]
  • |Middle Aged[MESH]
  • |Parvovirus B19, Human/*immunology[MESH]


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