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10.1093/infdis/170.4.802 http://scihub22266oqcxt.onion/10.1093/infdis/170.4.802 7930721!ä!7930721 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Infect+Dis 1994 ; 170 (4): 802-10 Nephropedia Template TP {{tp|p=7930721|t=1994. Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP |pdf=|usr=}}{{7930721}} gab.com Text Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP JO: J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=7930721 #FOAvip Despite increasing therapeutic use of interferon (IFN)-alpha, its effects on human neutrophil function are not well characterized. In vitro preincubation of neutrophils with recombinant IFN-alpha and -gamma, tumor necrosis factor (TNF), or granulocyte-macrophage colony-stimulating factor (GM-CSF) enhanced neutrophil respiratory burst responses to stimulation with influenza A virus (IAV) and FMLP. The enhancing effects of IFNs were more subtle and required more prolonged incubation than those of TNF and GM-CSF. TNF and GM-CSF enhanced neutrophil binding of IAV and neutrophil intracellular calcium and membrane depolarization responses to IAV or FMLP stimulation, while IFNs did not. Inhibitors of neutrophil tyrosine kinase activation and protein synthesis blocked IFN-alpha-induced enhancement of respiratory burst responses. In addition to its other well-characterized effects, IFN-alpha may protect against viral infection indirectly by promoting neutrophil respiratory burst responses. Twit Text FOAVip Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP ????J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=7930721 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=7930721 #FOAvip English Wikipedia <ref>{{Cite pmid|7930721}}</ref> Interferon-alpha enhances neutrophil respiratory burst responses to stimulation with influenza A virus and FMLP #MMPMID7930721 Little R; White MR; Hartshorn KL J Infect Dis 1994[Oct]; 170 (4): 802-10 PMID7930721show ga Despite increasing therapeutic use of interferon (IFN)-alpha, its effects on human neutrophil function are not well characterized. In vitro preincubation of neutrophils with recombinant IFN-alpha and -gamma, tumor necrosis factor (TNF), or granulocyte-macrophage colony-stimulating factor (GM-CSF) enhanced neutrophil respiratory burst responses to stimulation with influenza A virus (IAV) and FMLP. The enhancing effects of IFNs were more subtle and required more prolonged incubation than those of TNF and GM-CSF. TNF and GM-CSF enhanced neutrophil binding of IAV and neutrophil intracellular calcium and membrane depolarization responses to IAV or FMLP stimulation, while IFNs did not. Inhibitors of neutrophil tyrosine kinase activation and protein synthesis blocked IFN-alpha-induced enhancement of respiratory burst responses. In addition to its other well-characterized effects, IFN-alpha may protect against viral infection indirectly by promoting neutrophil respiratory burst responses. |Animals[MESH] |Calcium/blood[MESH] |Cell Adhesion[MESH] |Cell Line[MESH] |Chick Embryo[MESH] |Dogs[MESH] |Dose-Response Relationship, Drug[MESH] |Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology[MESH] |Humans[MESH] |Hydrogen Peroxide/blood[MESH] |In Vitro Techniques[MESH] |Influenza A virus/*physiology[MESH] |Interferon Type I/*pharmacology[MESH] |Interferon-gamma/*pharmacology[MESH] |Kidney[MESH] |Kinetics[MESH] |Luminescent Measurements[MESH] |N-Formylmethionine Leucyl-Phenylalanine/*pharmacology[MESH] |Neutrophils/drug effects/*physiology/virology[MESH] |Recombinant Proteins/pharmacology[MESH] |Respiratory Burst/drug effects/*physiology[MESH] |Superoxides/blood[MESH]Interferon-alpha enhances neutrophil respiratory burst responses to st(epmc).pdf DeepDyve Pubget Overpricing