Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

http://scihub22266oqcxt.onion/ 7528597!ä!7528597 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Mol+Biol+Res 1994 ; 40 (1): 35-9 Nephropedia Template TP {{tp|p=7528597|t=1994. Hypoxia regulatory elements of the human vascular endothelial growth factor gene |pdf=|usr=}}{{7528597}} gab.com Text Hypoxia regulatory elements of the human vascular endothelial growth factor gene JO: Cell Mol Biol Res http://www.kidney.de/pget.php?&tw=1&pmid=7528597 #FOAvip Vascular endothelial growth factor (VEGF) expression is highly stimulated by hypoxia, both in vitro and in vivo. Recent findings suggest that the VEGF gene utilizes an oxygen sensing mechanism similar to the one used by the erythropoietin gene. The genomic sequences that control the VEGF response to hypoxia are, however, largely unknown. In utilizing transient transfection assays in HeLa cells we determined that hypoxia/cobalt responsive enhancer elements are present at the 5' and 3' flanking regions of the human VEGF gene. The 3' enhancer is contained in a 160 bp fragment located about 60 bp downstream of the polyadenylation site. It contains a sequence stretch of about 12 bp which are highly homologous to sequences in the erythropoietin hypoxia-responsive enhancer. The 5' flanking enhancer is contained in a 100 bp fragment located about 800 bp upstream of the start site. This fragment does not contain significant homologies with the erythropoietin enhancer. Thus, it appears that the response to hypoxia of the VEGF gene is controlled by two regulatory elements; one which may be related to the erythropoietin enhancer and a second, which appears to be a completely unrelated sequence. Twit Text FOAVip Hypoxia regulatory elements of the human vascular endothelial growth factor gene ????Cell Mol Biol Res http://www.kidney.de/pget.php?&tw=1&pmid=7528597 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=7528597 #FOAvip English Wikipedia <ref>{{Cite pmid|7528597}}</ref> Hypoxia regulatory elements of the human vascular endothelial growth factor gene #MMPMID7528597 Minchenko A; Salceda S; Bauer T; Caro J Cell Mol Biol Res 1994[]; 40 (1): 35-9 PMID7528597show ga Vascular endothelial growth factor (VEGF) expression is highly stimulated by hypoxia, both in vitro and in vivo. Recent findings suggest that the VEGF gene utilizes an oxygen sensing mechanism similar to the one used by the erythropoietin gene. The genomic sequences that control the VEGF response to hypoxia are, however, largely unknown. In utilizing transient transfection assays in HeLa cells we determined that hypoxia/cobalt responsive enhancer elements are present at the 5' and 3' flanking regions of the human VEGF gene. The 3' enhancer is contained in a 160 bp fragment located about 60 bp downstream of the polyadenylation site. It contains a sequence stretch of about 12 bp which are highly homologous to sequences in the erythropoietin hypoxia-responsive enhancer. The 5' flanking enhancer is contained in a 100 bp fragment located about 800 bp upstream of the start site. This fragment does not contain significant homologies with the erythropoietin enhancer. Thus, it appears that the response to hypoxia of the VEGF gene is controlled by two regulatory elements; one which may be related to the erythropoietin enhancer and a second, which appears to be a completely unrelated sequence. |*Genes, Regulator/drug effects[MESH] |Base Sequence[MESH] |Cell Hypoxia/genetics[MESH] |Cobalt/pharmacology[MESH] |DNA/genetics[MESH] |Endothelial Growth Factors/*genetics[MESH] |Enhancer Elements, Genetic[MESH] |Erythropoietin/genetics[MESH] |HeLa Cells[MESH] |Humans[MESH] |Hypoxia/*genetics[MESH] |Lymphokines/*genetics[MESH] |Molecular Sequence Data[MESH] |Neovascularization, Pathologic/genetics[MESH] |Sequence Homology, Nucleic Acid[MESH] |Transfection[MESH] |Vascular Endothelial Growth Factor A[MESH]Hypoxia regulatory elements of the human vascular endothelial growth f(epmc).pdf DeepDyve Pubget Overpricing