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10.1111/j.1445-5994.1981.tb03516.x

http://scihub22266oqcxt.onion/10.1111/j.1445-5994.1981.tb03516.x
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7030293!ä!7030293

suck abstract from ncbi


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pmid7030293      Aust+N+Z+J+Med 1981 ; 11 (4): 380-2
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  • Glyoxalase phenotypes in patients with diabetes mellitus #MMPMID7030293
  • McCann VJ; Davis RE; Welborn TA; Constable IJ; Beale DG
  • Aust N Z J Med 1981[Aug]; 11 (4): 380-2 PMID7030293show ga
  • Caucasian diabetic patients in Australian surveys showed a significant difference in the distribution of glyoxalase phenotypes. Insulin dependent diabetic patients with age of onset less than 40 years had a relative excess of glyoxalase homozygote 1-1 and a deficiency of types 2-1 and 2-2. Non-insulin dependent diabetic patients were not significantly different from non-diabetic subjects in the distribution of glyoxalase phenotypes. Insulin dependent diabetic patients without the complications of retinopathy or neuropathy also showed a significant excess of glyoxalase type 1-1 in relation to the control group. Genes controlling glyoxalase polymorphism appear to be associated with the variations of diabetes and its complications.
  • |Australia[MESH]
  • |Diabetes Mellitus/drug therapy/*genetics[MESH]
  • |Diabetic Neuropathies/genetics[MESH]
  • |Diabetic Retinopathy/genetics[MESH]
  • |Ethnicity[MESH]
  • |HLA Antigens/genetics[MESH]
  • |Humans[MESH]
  • |Insulin/therapeutic use[MESH]
  • |Lactoylglutathione Lyase/*genetics[MESH]
  • |Lyases/*genetics[MESH]
  • |Phenotype[MESH]


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