Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/302426a0 http://scihub22266oqcxt.onion/10.1038/302426a0 6835376!ä!6835376 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nature 1983 ; 302 (5907): 426-9 Nephropedia Template TP {{tp|p=6835376|t=1983. A human parvovirus-like virus inhibits haematopoietic colony formation in vitro |pdf=|usr=}}{{6835376}} gab.com Text A human parvovirus-like virus inhibits haematopoietic colony formation in vitro JO: Nature http://www.kidney.de/pget.php?&tw=1&pmid=6835376 #FOAvip Viruses have been shown to cause bone marrow aplasia in animals and have been implicated in bone marrow failure in man; however, until recently, a specific link between human viral infection and bone marrow failure has not been proven. In 1975 Cossart and colleagues found a serum parvovirus-like virus (SPLV, sometimes referred to as B19) in human serum. Antibody to this virus is present in the sera of 30-45% of healthy adults (Y. E. Cossart, P. P. Mortimer, unpublished observations). However, evidence for a direct link came from work by Pattison et al. who found five children with transient aplastic crisis of sickle cell disease and evidence of active infection with SPLV. This association was later confirmed in a large series of children with sickle cell disease and aplastic crisis in Jamaica. We have studied the effects of virus-containing material on haematopoiesis, using in vitro colony-forming assays to look for direct evidence for a role of SPLV in bone marrow aplasia. We show here that SPLV-containing sera inhibit erythropoiesis in culture. Moreover, in a child with hereditary spherocytosis who developed transient aplastic crisis, a strong inhibitory effect of the patient's serum on erythropoiesis correlated with the presence of virus. Twit Text FOAVip A human parvovirus-like virus inhibits haematopoietic colony formation in vitro ????Nature http://www.kidney.de/pget.php?&tw=1&pmid=6835376 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=6835376 #FOAvip English Wikipedia <ref>{{Cite pmid|6835376}}</ref> A human parvovirus-like virus inhibits haematopoietic colony formation in vitro #MMPMID6835376 Mortimer PP; Humphries RK; Moore JG; Purcell RH; Young NS Nature 1983[Mar]; 302 (5907): 426-9 PMID6835376show ga Viruses have been shown to cause bone marrow aplasia in animals and have been implicated in bone marrow failure in man; however, until recently, a specific link between human viral infection and bone marrow failure has not been proven. In 1975 Cossart and colleagues found a serum parvovirus-like virus (SPLV, sometimes referred to as B19) in human serum. Antibody to this virus is present in the sera of 30-45% of healthy adults (Y. E. Cossart, P. P. Mortimer, unpublished observations). However, evidence for a direct link came from work by Pattison et al. who found five children with transient aplastic crisis of sickle cell disease and evidence of active infection with SPLV. This association was later confirmed in a large series of children with sickle cell disease and aplastic crisis in Jamaica. We have studied the effects of virus-containing material on haematopoiesis, using in vitro colony-forming assays to look for direct evidence for a role of SPLV in bone marrow aplasia. We show here that SPLV-containing sera inhibit erythropoiesis in culture. Moreover, in a child with hereditary spherocytosis who developed transient aplastic crisis, a strong inhibitory effect of the patient's serum on erythropoiesis correlated with the presence of virus. |Anemia, Aplastic/*microbiology[MESH] |Anemia, Hemolytic/etiology/microbiology[MESH] |Anemia, Sickle Cell/microbiology[MESH] |Hematopoiesis[MESH] |Hematopoietic Stem Cells/*microbiology[MESH] |Humans[MESH] |Parvoviridae/*physiology[MESH] |Spherocytosis, Hereditary/microbiology[MESH]A human parvovirus-like virus inhibits haematopoietic colony formation(epmc).pdf DeepDyve Pubget Overpricing