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10.1159/000163171

http://scihub22266oqcxt.onion/10.1159/000163171
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6403392!ä!6403392

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suck abstract from ncbi


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pmid6403392      Exp+Cell+Biol 1983 ; 51 (1): 39-43
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  • Phorbol myristate acetate-induced macrophage aggregation #MMPMID6403392
  • Badenoch-Jones P
  • Exp Cell Biol 1983[]; 51 (1): 39-43 PMID6403392show ga
  • Phorbol myristate acetate (PMA) at nanomole concentrations induces a rapid aggregation of guinea pig macrophages. This aggregation is dependent on extracellular Mg2+ (but not Ca2+) for its development. Additionally, it is inhibited by some agents which also inhibit aggregation induced by lymphokines and the ionophore A23187. Although the mechanism of aggregation has not been determined, it does not appear to be related to either arachidonic acid metabolites or products of the respiratory burst. In this respect, it resembles the PMA-induced aggregation of neutrophils.
  • |Animals[MESH]
  • |Calcimycin/pharmacology[MESH]
  • |Calcium/pharmacology[MESH]
  • |Cell Aggregation/drug effects[MESH]
  • |Guinea Pigs[MESH]
  • |Macrophages/*drug effects[MESH]
  • |Magnesium/pharmacology[MESH]
  • |Phorbols/*pharmacology[MESH]


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