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Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Nephrologie 1983 ; 4 (2): 60-3 Nephropedia Template TP
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Influence a court terme des thiazides sur le metabolisme du magnesium, du calcium et accessoirement sur celui du phosphore, de l'acide urique, de l'oxalate et de l'AMP cyclique #MMPMID6308488
Hodler J; Roulin F; Haldimann B
Nephrologie 1983[]; 4 (2): 60-3 PMID6308488show ga
Six healthy young volunteers were fed during two period of 9 days each by a strictly constantly liquid formula diet (Fresubin), on an ambulator basis. In a single blind cross-over randomized study, they were given either hydrochlorothiazide, 50 mg p.d., or a placebo during the first seven days of the two periods. The diuretic did not induce significant changes of either magnesemia or magnesiuria. In addition, the magnesium excretion after a challenging intravenous magnesium load remained unchanged. However, the thiazide normally increased the urinary excretion of sodium and potassium. It also induced hypocalciuria and hypercalcemia. The urinary excretion of cAMP and oxalic acid remained stable.