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10.1099/0022-1317-50-1-205 http://scihub22266oqcxt.onion/10.1099/0022-1317-50-1-205 6160200!ä!6160200 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Gen+Virol 1980 ; 50 (1): 205-10 Nephropedia Template TP {{tp|p=6160200|t=1980. Interferon-dependent genetic resistance to influenza virus in mice: virus replication in macrophages is inhibited at an early step |pdf=|usr=}}{{6160200}} gab.com Text Interferon-dependent genetic resistance to influenza virus in mice: virus replication in macrophages is inhibited at an early step JO: J Gen Virol http://www.kidney.de/pget.php?&tw=1&pmid=6160200 #FOAvip Inborn resistance to orthomyxoviruses due to the allele Mx was investigated at the molecular level in macrophages from A2G mice. In the absence of interferon, Mx-bearing and control cells were equally permissive for M-TUR, a macrophage-adapted strain of influenza A virus. After treatment with various doses of mouse interferon type I, Mx-bearing cells were fully resistant to this virus whereas cells lacking Mx were only marginally protected. Virus attachment and penetration were equally efficient in Mx-carrying and control cells and were not influenced by interferon. However, virus protein synthesis was blocked in Mx-bearing macrophages expressing resistance. These findings indicate that the resistance mechanism specific for influenza viruses realized by Mx in cooperation with interferon inhibits influenza virus replication in macrophages at an early stage following attachment and penetration of the virus. Twit Text FOAVip Interferon-dependent genetic resistance to influenza virus in mice: virus replication in macrophages is inhibited at an early step ????J Gen Virol http://www.kidney.de/pget.php?&tw=1&pmid=6160200 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=6160200 #FOAvip English Wikipedia <ref>{{Cite pmid|6160200}}</ref> Interferon-dependent genetic resistance to influenza virus in mice: virus replication in macrophages is inhibited at an early step #MMPMID6160200 Horisberger MA; Haller O; Arnheiter H J Gen Virol 1980[Sep]; 50 (1): 205-10 PMID6160200show ga Inborn resistance to orthomyxoviruses due to the allele Mx was investigated at the molecular level in macrophages from A2G mice. In the absence of interferon, Mx-bearing and control cells were equally permissive for M-TUR, a macrophage-adapted strain of influenza A virus. After treatment with various doses of mouse interferon type I, Mx-bearing cells were fully resistant to this virus whereas cells lacking Mx were only marginally protected. Virus attachment and penetration were equally efficient in Mx-carrying and control cells and were not influenced by interferon. However, virus protein synthesis was blocked in Mx-bearing macrophages expressing resistance. These findings indicate that the resistance mechanism specific for influenza viruses realized by Mx in cooperation with interferon inhibits influenza virus replication in macrophages at an early stage following attachment and penetration of the virus. |*Alleles[MESH] |*Immunity, Innate[MESH] |Animals[MESH] |Influenza A virus/*growth & development[MESH] |Interferons/*pharmacology[MESH] |Macrophages/*microbiology[MESH] |Mice[MESH] |Mice, Inbred CBA[MESH] |Mice, Inbred Strains[MESH] |Orthomyxoviridae Infections/immunology[MESH]Interferon-dependent genetic resistance to influenza virus in mice: vi(epmc).pdf DeepDyve Pubget Overpricing