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602148!ä!602148

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pmid602148      Vopr+Virusol 1977 ; ä (6): 698-703
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  • Elektronno-mikroskopicheskoe issledovanie vzaimodeistviia virusa grippa s peritoneal'nymi myshinymi makrofagami #MMPMID602148
  • Shushkov IS; Lazarenko VN; Kosiakov PN; Klimenko SM
  • Vopr Virusol 1977[Nov]; ä (6): 698-703 PMID602148show ga
  • Electron microscopic study of mouse peritoneal macrophages infected with influenza virus showed typical phenomena of phagocytosis (absorption, invagination of plasma membrane, and formation of phagosomes) to occur at early stages of virus-cell interaction, up to 2 hours. At later stages, from 3 to 24 hours postinfection, virus particles were completely absent and virus antigen was present in most cells indicating the distruction of phagocytized virus. These observations confirm an important role of macrophages in antiviral immunity.
  • |*Orthomyxoviridae[MESH]
  • |*Phagocytosis[MESH]
  • |Animals[MESH]
  • |Ascitic Fluid/cytology[MESH]
  • |In Vitro Techniques[MESH]
  • |Macrophages/*immunology/microbiology/ultrastructure[MESH]
  • |Mice[MESH]
  • |Microscopy, Electron[MESH]


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