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10.1038/s41598-025-30547-8

http://scihub22266oqcxt.onion/10.1038/s41598-025-30547-8
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41366278!?!41366278

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suck abstract from ncbi

pmid41366278      Sci+Rep 2025 ; ? (?): ?
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  • Colloidal stability and controlled release of Au@SiO(2) and Ag@SiO(2) core-shell nanostructures from biopolymer-based hydrogels #MMPMID41366278
  • Kowalska A; Adamska E; Wcislo A; Deja K; Kalinowska A; Grobelna B
  • Sci Rep 2025[Dec]; ? (?): ? PMID41366278show ga
  • Nanotechnology offers innovative strategies for developing multifunctional cosmetic ingredients. Here, we synthesize Au@SiO(2) and Ag@SiO(2) core-shell nanostructures with high shape and size uniformity, colloidal stability, and hydrophilicity. The silica shell stabilizes the metal core and enables surface functionalization, enhancing applicability in biopolymer-based formulations. We characterize the nanomaterials using UV-Vis spectroscopy, TEM, DLS, zeta potential, and contact angle measurements, confirming well-defined core-shell morphology and favorable surface properties. Both nanostructures display comparable antioxidant activity, while Ag@SiO(2) exhibits superior catalytic efficiency. To evaluate delivery performance, we incorporate the nanoparticles into sodium hyaluronate (HA) and hydroxyethylcellulose (HEC) hydrogels. The hybrid gels maintain homogenous morphology and enable tunable nanoparticle release profiles: HA gels promote rapid release and significantly improve skin hydration, whereas HEC gels provide sustained release suitable for prolonged action. These results demonstrate that Au@SiO(2) and Ag@SiO(2) nanostructures act as versatile, stable, and bioactive components for cosmetic and biomedical formulations. The study highlights the potential of core-shell nanomaterials at soft matter interfaces, combining antioxidant and antimicrobial functionality with controlled delivery and enhanced skin barrier performance.
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