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10.1007/s10840-025-02185-7 http://scihub22266oqcxt.onion/10.1007/s10840-025-02185-7 41359233!?!41359233 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=41359233&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Interv+Card+Electrophysiol 2025 ; ? (?): ? Nephropedia Template TP {{tp|p=41359233|t=2025. Comparative spatiotemporal neuromodulation effect between pulsed field and cryoballoon ablation for atrial fibrillation |pdf=|usr=}}{{41359233}} gab.com Text Comparative spatiotemporal neuromodulation effect between pulsed field and cryoballoon ablation for atrial fibrillation JO: J Interv Card Electrophysiol http://www.kidney.de/pget.php?&tw=1&pmid=41359233 #FOAvip BACKGROUND: Thermal ablation for atrial fibrillation (AF) exerts a variable additive cardiac neuromodulation effect, primarily via the right anterior ganglionated plexus (RAGP), located between the right superior pulmonary vein (RSPV) and superior vena cava (SVC). The impact of non-thermal pulsed field ablation (PFA) on neuromodulation remains unclear. Our objective was to compare the spatiotemporal neuromodulation effect between thermal and non-thermal AF ablation. METHODS: Consecutive paroxysmal AF patients undergoing either first-time cryoballoon ablation (CBA) or PFA with pre-procedural cardiac computed tomography (CT) were evaluated. Anatomic CT evaluation included measurement of the shortest distance between RSPV and SVC (RSPV-SVC distance). Changes in heart rate (HR) were assessed via electrocardiograms during and after ablation. RESULTS: A total of 280 patients (CBA, n = 210; PFA, n = 70) were included, with similar baseline characteristics between both groups. Significant intraprocedural HR increase (DeltaHR >/= 15 bpm) was observed in 116 patients: CBA (n = 88, 42%), PFA (n = 28, 40%), p = 0.779. Although there was no difference in baseline HR between CBA vs PFA groups, HR at the end of the procedure was higher only in CBA group (75 +/- 11 bpm vs 66 +/- 11 bpm; p < 0.001). Multivariable analysis identified the RSPV-SVC distance (OR 0.607; 95% CI 0.445-0.775; p < 0.001) and younger age (OR 0.950; 95% CI 0.905-0.993; p = 0.030) as independent predictors of an intraprocedural DeltaHR >/= 15 bpm. CONCLUSION: Both CBA and PFA for AF modulate the RAGP, particularly in patients with a shorter RSPV-SVC distance. However, neuromodulation with PFA is only transient during the procedure. Twit Text FOAVip Comparative spatiotemporal neuromodulation effect between pulsed field and cryoballoon ablation for atrial fibrillation ????J Interv Card Electrophysiol http://www.kidney.de/pget.php?&tw=1&pmid=41359233 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41359233 #FOAvip English Wikipedia <ref>{{Cite pmid|41359233}}</ref> Comparative spatiotemporal neuromodulation effect between pulsed field and cryoballoon ablation for atrial fibrillation #MMPMID41359233 Nakasone K; Tanaka K; Del Monte A; Della Rocca DG; Pannone L; Vetta G; Overeinder I; Bala G; Sorgente A; Sieira J; Almorad A; Brugada P; Sarkozy A; Chierchia GB; de Asmundis C; Stroker E J Interv Card Electrophysiol 2025[Dec]; ? (?): ? PMID41359233show ga BACKGROUND: Thermal ablation for atrial fibrillation (AF) exerts a variable additive cardiac neuromodulation effect, primarily via the right anterior ganglionated plexus (RAGP), located between the right superior pulmonary vein (RSPV) and superior vena cava (SVC). The impact of non-thermal pulsed field ablation (PFA) on neuromodulation remains unclear. Our objective was to compare the spatiotemporal neuromodulation effect between thermal and non-thermal AF ablation. METHODS: Consecutive paroxysmal AF patients undergoing either first-time cryoballoon ablation (CBA) or PFA with pre-procedural cardiac computed tomography (CT) were evaluated. Anatomic CT evaluation included measurement of the shortest distance between RSPV and SVC (RSPV-SVC distance). Changes in heart rate (HR) were assessed via electrocardiograms during and after ablation. RESULTS: A total of 280 patients (CBA, n = 210; PFA, n = 70) were included, with similar baseline characteristics between both groups. Significant intraprocedural HR increase (DeltaHR >/= 15 bpm) was observed in 116 patients: CBA (n = 88, 42%), PFA (n = 28, 40%), p = 0.779. Although there was no difference in baseline HR between CBA vs PFA groups, HR at the end of the procedure was higher only in CBA group (75 +/- 11 bpm vs 66 +/- 11 bpm; p < 0.001). Multivariable analysis identified the RSPV-SVC distance (OR 0.607; 95% CI 0.445-0.775; p < 0.001) and younger age (OR 0.950; 95% CI 0.905-0.993; p = 0.030) as independent predictors of an intraprocedural DeltaHR >/= 15 bpm. CONCLUSION: Both CBA and PFA for AF modulate the RAGP, particularly in patients with a shorter RSPV-SVC distance. However, neuromodulation with PFA is only transient during the procedure. ?Comparative spatiotemporal neuromodulation effect between pulsed field(epmc).pdf DeepDyve Pubget Overpricing