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10.1007/s10522-025-10363-3 http://scihub22266oqcxt.onion/10.1007/s10522-025-10363-3 41359200!?!41359200 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=41359200&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Biogerontology 2025 ; 27 (1): 14 Nephropedia Template TP {{tp|p=41359200|t=2025. Effect of high-intensity interval training and resistance training on the follistatin and myostatin levels in gastrocnemius muscle of aged female rats |pdf=|usr=}}{{41359200}} gab.com Text Effect of high-intensity interval training and resistance training on the follistatin and myostatin levels in gastrocnemius muscle of aged female rats JO: Biogerontology http://www.kidney.de/pget.php?&tw=1&pmid=41359200 #FOAvip Myostatin and follistatin are the regulators of muscle growth and pivotal proteins that regulate muscle tissue function. An integrated approach is HIIT and resistance training provides a holistic strategy for promoting healthy aging and maintaining functional abilities, potentially through the modulation of myostatin and follistatin levels. This study aims to assess the effect of high-intensity interval training and resistance training on myostatin and follistatin protein concentrations in aged rats' serum and muscle tissue. In this study, 20-month-old female Sprague-Dawley rats were used in three groups: (1) Control (Con), (2) Resistance training (RT), and (3) High-intensity interval training (HIIT). The HIIT and resistance training protocols were carried out for 8 weeks and three sessions per week. The results showed serum levels and muscle tissue content of myostatin increased in the RT compared to the control group (p = 0.0001 and p = 0.04). The muscle tissue content of follistatin increased in the HIIT compared to the control group (p = 0.03). There is a significant difference in serum levels and muscle tissue content of follistatin between HIIT and RT groups (p = 0.0001 and p = 0.001). According to the roles of myostatin and follistatin in regulating muscle hypertrophy, present research shows HIIT has more effects on follistatin levels and resistance training has more effects on myostatin levels. This can indicate that according to the number of training sessions, HIIT can be a better and newer treatment method for older people. Twit Text FOAVip Effect of high-intensity interval training and resistance training on the follistatin and myostatin levels in gastrocnemius muscle of aged female rats ????Biogerontology http://www.kidney.de/pget.php?&tw=1&pmid=41359200 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41359200 #FOAvip English Wikipedia <ref>{{Cite pmid|41359200}}</ref> Effect of high-intensity interval training and resistance training on the follistatin and myostatin levels in gastrocnemius muscle of aged female rats #MMPMID41359200 Asadpour SM; Daryanoosh F; Zarifkar AH Biogerontology 2025[Dec]; 27 (1): 14 PMID41359200show ga Myostatin and follistatin are the regulators of muscle growth and pivotal proteins that regulate muscle tissue function. An integrated approach is HIIT and resistance training provides a holistic strategy for promoting healthy aging and maintaining functional abilities, potentially through the modulation of myostatin and follistatin levels. This study aims to assess the effect of high-intensity interval training and resistance training on myostatin and follistatin protein concentrations in aged rats' serum and muscle tissue. In this study, 20-month-old female Sprague-Dawley rats were used in three groups: (1) Control (Con), (2) Resistance training (RT), and (3) High-intensity interval training (HIIT). The HIIT and resistance training protocols were carried out for 8 weeks and three sessions per week. The results showed serum levels and muscle tissue content of myostatin increased in the RT compared to the control group (p = 0.0001 and p = 0.04). The muscle tissue content of follistatin increased in the HIIT compared to the control group (p = 0.03). There is a significant difference in serum levels and muscle tissue content of follistatin between HIIT and RT groups (p = 0.0001 and p = 0.001). According to the roles of myostatin and follistatin in regulating muscle hypertrophy, present research shows HIIT has more effects on follistatin levels and resistance training has more effects on myostatin levels. This can indicate that according to the number of training sessions, HIIT can be a better and newer treatment method for older people. |*Aging/metabolism[MESH] |*Follistatin/metabolism/blood[MESH] |*High-Intensity Interval Training/methods[MESH] |*Muscle, Skeletal/metabolism[MESH] |*Myostatin/metabolism/blood[MESH] |*Physical Conditioning, Animal/methods[MESH] |*Resistance Training/methods[MESH] |Animals[MESH] |Female[MESH] |Rats[MESH]Effect of high-intensity interval training and resistance training on (epmc).pdf DeepDyve Pubget Overpricing