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10.1002/cbdv.202500865 http://scihub22266oqcxt.onion/10.1002/cbdv.202500865 41355667!?!41355667 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=41355667&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Chem+Biodivers 2025 ; ? (?): e00865 Nephropedia Template TP {{tp|p=41355667|t=2025. Synergistic Effect of Bovine Serum Albumin-Gold Nanoclusters Against Antibiotic-Resistant Bacterial Sustainability and Biofilm Fabrication |pdf=|usr=}}{{41355667}} gab.com Text Synergistic Effect of Bovine Serum Albumin-Gold Nanoclusters Against Antibiotic-Resistant Bacterial Sustainability and Biofilm Fabrication JO: Chem Biodivers http://www.kidney.de/pget.php?&tw=1&pmid=41355667 #FOAvip This study evaluated the antimicrobial and antibiofilm effects of bovine serum albumin-gold nanoclusters (BSA-GNCs) against planktonic and antibiotic-resistant bacteria. BSA-GNCs were synthesized and characterized using UV spectrofluorimetry, Fourier transform infrared spectroscopy (FTIR), zeta sizing, scanning electron microscopy (SEM)-energy-dispersive x-ray (EDX), and transmission electron microscopy (TEM) analyses. Cytotoxicity was evaluated using the MTT assay. Antimicrobial and antibiofilm activities were assessed against four bacterial strains: Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis. A characteristic UV absorption peak at 500 nm, along with a visible color change, confirmed successful GNC formation. FTIR spectra showed prominent functional groups at 598.33, 1102.79, 1261.21, 1637.84, 2923.54, and 3430.76 cm(-1), and the mean hydrodynamic diameter measured 22.72 nm. BSA-GNC exposure induced moderate cytotoxicity in HaCaT cells at concentrations above 40 microg/microL. Treatment with 40 microg/microL BSA-GNCs significantly enhanced bacterial growth inhibition zones (KP: 28 +/- 2.44 mm; SA: 27.5 +/- 2.45 mm; PA: 31.5 +/- 1.91 mm; EF: 29.75 +/- 2.5 mm) after 24 h. TEM imaging of BSA-GNC-treated bacteria revealed shrunken, disrupted cells with degenerated cytoplasm. Additionally, BSA-GNC treatment markedly reduced biofilm formation at both 24 and 48 h compared with untreated controls. These findings indicate that BSA-GNCs enhance reactive oxygen species (ROS) accumulation, leading to impaired bacterial growth and biofilm formations. Twit Text FOAVip Synergistic Effect of Bovine Serum Albumin-Gold Nanoclusters Against Antibiotic-Resistant Bacterial Sustainability and Biofilm Fabrication ????Chem Biodivers http://www.kidney.de/pget.php?&tw=1&pmid=41355667 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=41355667 #FOAvip English Wikipedia <ref>{{Cite pmid|41355667}}</ref> Synergistic Effect of Bovine Serum Albumin-Gold Nanoclusters Against Antibiotic-Resistant Bacterial Sustainability and Biofilm Fabrication #MMPMID41355667 Alanazi MA; Samivel R; Almubrad T; Khan AA; Masmali A; Alanazi SA; Akhtar S Chem Biodivers 2025[Dec]; ? (?): e00865 PMID41355667show ga This study evaluated the antimicrobial and antibiofilm effects of bovine serum albumin-gold nanoclusters (BSA-GNCs) against planktonic and antibiotic-resistant bacteria. BSA-GNCs were synthesized and characterized using UV spectrofluorimetry, Fourier transform infrared spectroscopy (FTIR), zeta sizing, scanning electron microscopy (SEM)-energy-dispersive x-ray (EDX), and transmission electron microscopy (TEM) analyses. Cytotoxicity was evaluated using the MTT assay. Antimicrobial and antibiofilm activities were assessed against four bacterial strains: Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis. A characteristic UV absorption peak at 500 nm, along with a visible color change, confirmed successful GNC formation. FTIR spectra showed prominent functional groups at 598.33, 1102.79, 1261.21, 1637.84, 2923.54, and 3430.76 cm(-1), and the mean hydrodynamic diameter measured 22.72 nm. BSA-GNC exposure induced moderate cytotoxicity in HaCaT cells at concentrations above 40 microg/microL. Treatment with 40 microg/microL BSA-GNCs significantly enhanced bacterial growth inhibition zones (KP: 28 +/- 2.44 mm; SA: 27.5 +/- 2.45 mm; PA: 31.5 +/- 1.91 mm; EF: 29.75 +/- 2.5 mm) after 24 h. TEM imaging of BSA-GNC-treated bacteria revealed shrunken, disrupted cells with degenerated cytoplasm. Additionally, BSA-GNC treatment markedly reduced biofilm formation at both 24 and 48 h compared with untreated controls. These findings indicate that BSA-GNCs enhance reactive oxygen species (ROS) accumulation, leading to impaired bacterial growth and biofilm formations. ?Synergistic Effect of Bovine Serum Albumin-Gold Nanoclusters Against (epmc).pdf DeepDyve Pubget Overpricing