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suck abstract from ncbi


10.1038/s41523-025-00864-2

http://scihub22266oqcxt.onion/10.1038/s41523-025-00864-2
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41345397!?!41345397

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suck abstract from ncbi

pmid41345397      NPJ+Breast+Cancer 2025 ; ? (?): ?
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  • Optimizing clinical monitoring and management guidelines for capivasertib in HR-positive/HER2-negative advanced breast cancer: expert opinion #MMPMID41345397
  • Iyengar NM; O'Shaughnessy JA; Moore HB; Hamilton E; Jhaveri KL; Ma CX; Tedesco K; Vasekar M; Donahue S; Rugo HS
  • NPJ Breast Cancer 2025[Dec]; ? (?): ? PMID41345397show ga
  • Capivasertib, an AKT inhibitor, approved in combination with fulvestrant for hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer with >/=1 PIK3CA, AKT1, and/or PTEN alterations, significantly improved progression-free survival in the CAPItello-291 phase 3 trial. However, capivasertib-associated adverse events of diarrhea, rash, and hyperglycemia may require proactive management. This article provides practical recommendations to support prevention and early intervention to optimize adherence and treatment outcomes.
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