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10.1136/bmjopen-2025-101560 http://scihub22266oqcxt.onion/10.1136/bmjopen-2025-101560 40908016!12414204!40908016     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 298.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\40908016.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMJ+Open 2025 ; 15 (9): e101560 Nephropedia Template TP {{tp|p=40908016|t=2025. Factors influencing reproductive concerns and their correlation with quality of life among adolescents and young adults with acute leukaemia in Hunan province, China: a cross-sectional study |pdf=|usr=}}{{40908016}} gab.com Text Factors influencing reproductive concerns and their correlation with quality of life among adolescents and young adults with acute leukaemia in Hunan province, China: a cross-sectional study JO: BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=40908016 #FOAvip OBJECTIVE: This study aimed to examine the reproductive concerns and their influencing factors among adolescents and young adults with acute leukaemia and to explore the relationship between reproductive concerns and patients' quality of life. DESIGN: A cross-sectional study. SETTING: The haematology departments of four tertiary-level hospitals in Hunan province, China. PARTICIPANTS: Convenience sampling method was used to recruit 233 adolescents and young adults with acute leukaemia, from June 2024 to December 2024. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was assessed using the Chinese version of the Reproductive Concerns After Cancer and the secondary outcome was measured by the 12-item Short Form Health Survey. RESULTS: Adolescents and young adults with acute leukaemia had a mean reproductive concerns score of 55.57+/-7.57, a quality of life physical component summary (PCS) score of 38.54+/-8.58 and a mental component summary (MCS) score of 39.84+/-8.78. Univariate analysis showed significant differences in reproductive concerns based on fertility status, place of residence, education level, fertility counselling and family history of acute leukaemia (p<0.05). Multiple linear regression analysis revealed already childbearing (beta=-0.169, p=0.009), a high education level (beta=-0.256, p=0.020), rural residence (beta=0.183, p=0.006), receipt of fertility counselling (beta=0.161, p=0.012) and family history (beta=0.139, p=0.029) as independent risk factors for reproductive concerns. Spearman correlation analysis showed no significant correlation between reproductive concerns and the PCS but revealed a significant negative correlation between reproductive concerns and the MCS (beta=-0.170, p<0.01). CONCLUSION: Adolescents and young adults with acute leukaemia exhibited moderately high levels of reproductive concerns, particularly those who had no children, had a low education level, resided in rural areas, had a family history of acute leukaemia or had received fertility counselling. Therefore, we suggest that healthcare providers prioritise addressing reproductive concerns in high-risk patients by offering tailored, high-quality and continuous fertility counselling and psychological support. Strengthening these strategies can help alleviate reproductive concerns and improve both mental health and overall quality of life in this population. Twit Text FOAVip Factors influencing reproductive concerns and their correlation with quality of life among adolescents and young adults with acute leukaemia in Hunan province, China: a cross-sectional study ????BMJ Open http://www.kidney.de/pget.php?&tw=1&pmid=40908016 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=40908016 #FOAvip English Wikipedia <ref>{{Cite pmid|40908016}}</ref> Factors influencing reproductive concerns and their correlation with quality of life among adolescents and young adults with acute leukaemia in Hunan province, China: a cross-sectional study #MMPMID40908016 Zhang Y; Zhang Z; Zhang W; Zeng X; Ma G; Xiao Y; Wong CL; Chan CWH; Gu C BMJ Open 2025[Sep]; 15 (9): e101560 PMID40908016show ga OBJECTIVE: This study aimed to examine the reproductive concerns and their influencing factors among adolescents and young adults with acute leukaemia and to explore the relationship between reproductive concerns and patients' quality of life. DESIGN: A cross-sectional study. SETTING: The haematology departments of four tertiary-level hospitals in Hunan province, China. PARTICIPANTS: Convenience sampling method was used to recruit 233 adolescents and young adults with acute leukaemia, from June 2024 to December 2024. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was assessed using the Chinese version of the Reproductive Concerns After Cancer and the secondary outcome was measured by the 12-item Short Form Health Survey. RESULTS: Adolescents and young adults with acute leukaemia had a mean reproductive concerns score of 55.57+/-7.57, a quality of life physical component summary (PCS) score of 38.54+/-8.58 and a mental component summary (MCS) score of 39.84+/-8.78. Univariate analysis showed significant differences in reproductive concerns based on fertility status, place of residence, education level, fertility counselling and family history of acute leukaemia (p<0.05). Multiple linear regression analysis revealed already childbearing (beta=-0.169, p=0.009), a high education level (beta=-0.256, p=0.020), rural residence (beta=0.183, p=0.006), receipt of fertility counselling (beta=0.161, p=0.012) and family history (beta=0.139, p=0.029) as independent risk factors for reproductive concerns. Spearman correlation analysis showed no significant correlation between reproductive concerns and the PCS but revealed a significant negative correlation between reproductive concerns and the MCS (beta=-0.170, p<0.01). CONCLUSION: Adolescents and young adults with acute leukaemia exhibited moderately high levels of reproductive concerns, particularly those who had no children, had a low education level, resided in rural areas, had a family history of acute leukaemia or had received fertility counselling. Therefore, we suggest that healthcare providers prioritise addressing reproductive concerns in high-risk patients by offering tailored, high-quality and continuous fertility counselling and psychological support. Strengthening these strategies can help alleviate reproductive concerns and improve both mental health and overall quality of life in this population. |*Leukemia/psychology[MESH] |*Quality of Life[MESH] |Adolescent[MESH] |Adult[MESH] |China/epidemiology[MESH] |Cross-Sectional Studies[MESH] |Female[MESH] |Fertility[MESH] |Humans[MESH] |Male[MESH]Factors influencing reproductive concerns and their correlation with q(epmc).pdf DeepDyve Pubget Overpricing